N-(4-Chlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide CAS 477857-82-2
| CAS No. | 477857-82-2 |
| Molecular Formula | C15H10ClN3OS |
| Molecular Weight | 315.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(4-Chlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide (CAS 477857-82-2), molecular formula C15H10ClN3OS and molecular weight 315.78 g/mol, is a CATO reference standard with documented purity and traceability.
N-(4-Chlorophenyl)-4-phenyl-1,2,3-thiadiazole-5-carboxamide (C15H10ClN3OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H10ClN3OS |
| Molecular Weight | 315.78 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related N Standards
- N-(5-(2-Chlorophenyl)-1,3,4-thiadiazol-2-yl)benzamide (CAS 137343-74-9)
- N-(4-chlorophenyl)-2-(pyridin-4-yl)thiazole-4-carboxamide (CAS 286860-10-4)
- 2-(2-(4-Chlorophenyl)thiazol-4-yl)benzoic acid (CAS 1092296-80-4)
- 1-{2-[(4-chlorophenyl)sulfanyl]phenyl}-2,5-dihydro-1H-pyrrole-2,5-dione (CAS 568550-95-8)
- 4-(4-(4-Chlorophenyl)thiazol-2-yl)benzoic acid (CAS 254911-27-8)
- 4-[4-(2-Chlorophenyl)-1,3-thiazol-2-yl]benzoic acid (CAS 338396-92-2)
- (2-Chlorophenyl)(3-(4-methoxyphenyl)pyrrolidin-1-yl)methanone (CAS 1208686-09-2)
- 2-(2-Chlorophenyl)-1-(2-phenylmorpholino)ethan-1-one (CAS 1210188-61-6)
Recommended Standards
- Nerandomilast Impurity 35 (CAS CATO-C4X-347335)
- Ethyl 2-[2-(aminocarbonyl)hydrazono]-3-[(4-chlorophenyl)sulfanyl]propanoate (CAS 886361-57-5)
- N-(5-Chloro-2-hydroxyphenyl)-1-phenylcyclopentane-1-carboxamide (CAS 1022206-23-0)
- 5-Chloro-9,10-dimethyl-8H-thieno[2',3':4,5]pyrimido[2,1-a]phthalazin-8-one (CAS 315676-39-2)
- 4-(Dimethylamino)-2-hydroxynicotinonitrile (CAS 62321-91-9)
- 1-((1-Ethyl-1h-pyrazol-4-yl)methyl)cyclopropane-1-carboxylic acid (CAS 1489897-06-4)
- N-Methoxy-N,3-dimethylfuran-2-carboxamide (CAS 342601-18-7)
- Cyclobutylmethanethiol (CAS 1352077-18-9)
- 3-((4-Fluorobenzyl)oxy)-4-methoxybenzaldehyde (CAS 351066-28-9)
- 2-(2-(Cyclopentylamino)ethoxy)ethan-1-ol (CAS 1042620-08-5)
- 1-Bromo-2-chloro-5-nitro-4-(trifluoromethyl)benzene (CAS 2167346-05-4)
- Methyl 2-(5-oxopyrrolidin-2-yl)acetate (CAS 82435-96-9)
- 5-[(4-nitrophenyl)methyl]-1H-1,2,3,4-tetrazole (CAS 131090-44-3)
- (10-31)Semaglutide (CAS CATO-C4X-2226283)
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