2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate CAS 477857-90-2

Purity 97%+In StockPharmaceutical Standards
CAS No.477857-90-2
Molecular FormulaC18H17F3N2O4
Molecular Weight382.33 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate CAS 477857-90-2 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate.

2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate (CAS 477857-90-2), molecular formula C18H17F3N2O4 and molecular weight 382.33 g/mol, is a CATO reference standard with documented purity and traceability.

Structurally, 2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate (C18H17F3N2O4) contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 10.0, corresponding to approximately 10 ring(s) or double-bond equivalent(s). With a molecular weight of 382.33 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), 2,2,2-Trifluoroethyl N-({4-[(4-methoxyphenyl)carbamoyl]phenyl}methyl)carbamate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC18H17F3N2O4
Molecular Weight382.33 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)10.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms2

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