1-[3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]pyrrolidine CAS 477857-95-7
| CAS No. | 477857-95-7 |
| Molecular Formula | C16H16ClNOS2 |
| Molecular Weight | 337.89 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-[3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]pyrrolidine.
1-[3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]pyrrolidine (CAS 477857-95-7), molecular formula C16H16ClNOS2 and molecular weight 337.89 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-[3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]pyrrolidine (C16H16ClNOS2) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 337.89 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 1-[3-(4-Chlorophenyl)-5-(methylsulfanyl)thiophene-2-carbonyl]pyrrolidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H16ClNOS2 |
| Molecular Weight | 337.89 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Chlorophenyl Standards
- 2-((4-Chlorophenyl)thio)-N-(2-(phenylthio)ethyl)acetamide (CAS 337923-35-0)
- 2-(2-((3-Chlorophenyl)amino)thiazol-4-yl)-N-isopentylacetamide (CAS 1040657-07-5)
- 1-(2-(2-Chlorophenyl)-2-(dimethylamino)ethyl)-3-(thiophen-2-ylmethyl)urea (CAS 1206994-32-2)
- N-(2-((5-(4-Chlorophenyl)-1H-imidazol-2-yl)thio)ethyl)pivalamide (CAS 897456-52-9)
- (E)-[(6-{[(4-chlorophenyl)methyl]sulfanyl}imidazo[2,1-b][1,3]thiazol-5-yl)methylidene](methoxy)amine (CAS 339023-29-9)
- Methyl ((4-chlorophenyl)sulfonyl)methioninate (CAS 1396966-21-4)
- 3-{[(3-chlorophenyl)methyl]sulfanyl}-4H-1lambda6,4-benzothiazine-1,1-dione (CAS 477868-91-0)
- Ethyl ((3-chlorophenyl)(2-oxocyclooctyl)methyl)carbamate (CAS 478064-01-6)
Recommended Standards
- 1,4-Dibromo-3,5-difluoro-2-(difluoromethoxy)benzene (CAS 1806353-79-6)
- 1,3-Dibromo-5-fluoro-2-(trifluoromethoxy)benzene (CAS 1806351-54-1)
- NSC-13755 (CAS 5430-24-0)
- 1,4-Dibromo-2,5-difluoro-3-(difluoromethoxy)benzene (CAS 1806347-91-0)
- 2,6-Dibromo-4-tert-butylphenylisothiocyanate (CAS 1000572-33-7)
- (S)-Methyl 2-(pyrrolidin-2-yl)-1H-benzo[d]imidazole-5-carboxylate dihydrochloride (CAS 1439922-01-6)
- 2-Bromo-6-methoxyimidazo[1,2-a]pyridine (CAS 1042141-33-2)
- 2-(4-Methoxy-benzyl)-piperidine hydrochloride (CAS 420137-09-3)
- 4-Bromo-2-(tetrahydro-2H-pyran-2-yl)-2H-indazole (CAS 1266386-31-5)
- 6-(4-Chlorophenyl)-1,3-dimethyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 886503-59-9)
- N-(imidazo[1,2-a]pyridin-5-yl)pivalamide (CAS 1242268-22-9)
- 1-Bromo-5-nitrophthalazine (CAS 1823331-63-0)
- 1,2-Bis(4'-methyl-[2,2'-bipyridin]-4-yl)ethane (CAS 96897-04-0)
- Fibrinogen-Binding Peptide (CAS 137235-80-4)
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