3-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-5-(methylthio)thiophene-2-carboxamide CAS 477857-97-9
| CAS No. | 477857-97-9 |
| Molecular Formula | C18H12ClF2NOS2 |
| Molecular Weight | 395.87 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies 3-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-5-(methylthio)thiophene-2-carboxamide (CAS 477857-97-9), a certified reference material (molecular formula C18H12ClF2NOS2, MW 395.87 g/mol) for analytical method development and quality control.
Structurally, 3-(4-Chlorophenyl)-N-(2,4-difluorophenyl)-5-(methylthio)thiophene-2-carboxamide (C18H12ClF2NOS2) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 395.87 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C18H12ClF2NOS2 |
| Molecular Weight | 395.87 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
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