3-(4-Hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)propanoic acid CAS 477858-45-0

Purity 97%+In StockPharmaceutical Standards
CAS No.477858-45-0
Molecular FormulaC17H15NO4
Molecular Weight297.31 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4-Hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)propanoic acid CAS 477858-45-0 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

3-(4-Hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)propanoic acid (CAS 477858-45-0), molecular formula C17H15NO4 and molecular weight 297.31 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of 3-(4-Hydroxyphenyl)-2-(1-oxoisoindolin-2-yl)propanoic acid (C17H15NO4) is characterized by a flavonoid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC17H15NO4
Molecular Weight297.31 g/mol
AppearancePale yellow to yellow crystalline powder
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in methanol, acetonitrile, DMSO, water (slightly soluble)
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)11.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms1

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