1-(1-(3,5-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)-2,2-dimethoxyethan-1-one CAS 477858-60-9
| CAS No. | 477858-60-9 |
| Molecular Formula | C12H11Cl2N3O3 |
| Molecular Weight | 316.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(1-(3,5-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)-2,2-dimethoxyethan-1-one.
1-(1-(3,5-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)-2,2-dimethoxyethan-1-one (CAS 477858-60-9), molecular formula C12H11Cl2N3O3 and molecular weight 316.14 g/mol, is a CATO reference standard with documented purity and traceability.
1-(1-(3,5-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)-2,2-dimethoxyethan-1-one (C12H11Cl2N3O3) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(1-(3,5-Dichlorophenyl)-1H-1,2,3-triazol-4-yl)-2,2-dimethoxyethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C12H11Cl2N3O3 |
| Molecular Weight | 316.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related Dichlorophenyl Standards
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- 8-[(E)-2-[(2,3-Dichlorophenyl)methylidene]hydrazin-1-yl]quinoline (CAS 478258-68-3)
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Recommended Standards
- (2-Iodophenyl)(piperazin-1-yl)methanone (CAS 926221-60-5)
- (1-Tosyl-1H-pyrrolo[2,3-β]pyridin-3-yl)boronic acid (CAS 882562-39-2)
- 2,4-Dichloro-6-(dibenzo[b,d]furan-3-yl)-1,3,5-triazine (CAS 2102042-41-9)
- (1-Tosyl-1H-pyrrolo[2,3-b]pyridin-2-yl)boronic acid (CAS 2096334-98-2)
- dibenzyl (5-bromo-1,3-phenylene)dicarbamate (CAS CATO-C3D-262401)
- 2-((3-Carbamoylphenyl)carbamoyl)benzoic acid (CAS 306325-55-3)
- 7-Isobutyl-1,2,3,4-tetrahydropyrido[2,3-d]pyridazin-8(7H)-one (CAS 1447961-38-7)
- n-(3-Amino-4-chlorophenyl)propanamide (CAS 213831-01-7)
- 2-(Piperazin-1-yl)quinoline-6-carbonitrile (CAS 160006-48-4)
- 2-(Phenoxymethyl)pyrrolidine (CAS 383127-73-9)
- 2-(Naphthalen-1-yl)pyrrolidine hydrochloride (CAS 1197235-46-3)
- N-(2-ethoxyphenyl)-N-(2-(4-methylpiperidin-1-yl)-2-oxoethyl)methanesulfonamide (CAS 700859-06-9)
- Ethyl 4-(pyrimidin-2-ylamino)benzoate (CAS 959928-89-3)
- Liraglutide Impurity 13 TFA Salt (CAS CATO-C4X-199213)
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