(E)-Methoxy({2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene})amine CAS 477859-36-2
| CAS No. | 477859-36-2 |
| Molecular Formula | C21H18F4N2O3S |
| Molecular Weight | 454.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 454.44 g/mol gives (E)-Methoxy({2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene})amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
(E)-Methoxy({2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene})amine (CAS 477859-36-2), molecular formula C21H18F4N2O3S and molecular weight 454.44 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution, (E)-Methoxy({2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene})amine is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 454.44 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (E)-Methoxy({2,2,2-trifluoro-1-[1-(4-fluorophenyl)-5-(4-methanesulfonylphenyl)-2-methyl-1H-pyrrol-3-yl]ethylidene})amine meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C21H18F4N2O3S |
| Molecular Weight | 454.44 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
- 4-{3-[3-methoxy-4-(propan-2-yloxy)phenyl]-1,2,4-oxadiazol-5-yl}-2-phenyl-1,2-dihydrophthalazin-1-one (CAS 1707728-03-7)
- Tris(4-methoxy-3,5-dimethylphenyl)phosphine (CAS 121898-64-4)
- 5-Methoxy-2-((tosyloxy)methyl)tetrahydrofuran-3-yl 4-methylbenzenesulfonate (CAS 60110-72-7)
- 6-Methoxy-2-methyl-3-(3,4,5-trimethoxybenzoyl)benzofuran-7-yl dihydrogen phosphate (CAS 945772-45-2)
- 3-Methoxy-4-Hydroxyclomiphene (CAS 117095-59-7)
- N-(2-methoxy-5-methylphenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-21-0)
- 4-Methoxy-N-(1-(4-methoxybenzyl)-5,6-dimethyl-1H-benzo[d]imidazol-4-yl)benzenesulfonamide (CAS 338954-91-9)
- 4-Methoxy-N-{1-[(3-methoxyphenyl)methyl]-5,6-dimethyl-1H-1,3-benzodiazol-4-yl}benzene-1-sulfonamide (CAS 338955-15-0)
Recommended Standards
- 2,7-Bis(3,5-dimethyl-1H-pyrazol-4-yl)benzo[lmn][3,8]phenanthroline-1,3,6,8(2H,7H)-tetraone (CAS 1521159-33-0)
- 1-(3-Methoxybenzyl)-3-methyl-4-(3-(trifluoromethyl)benzoyl)-3,4-dihydroquinoxalin-2(1H)-one (CAS 317833-51-5)
- Aminopterin-α-hyrazide (CAS 118359-33-4)
- 1,4-Bis(2-(benzo[d][1,3]dioxol-5-ylmethylene)hydrazinyl)phthalazine (CAS 27704-20-7)
- 1,8-Dinitroanthraquinone (CAS 129-39-5)
- Ethyl 4-chloro-7-fluoro-6-methoxyquinoline-3-carboxylate (CAS 311346-71-1)
- (E)-2-(2-((6-(2-Cyanophenoxy)pyrimidin-4-yl)oxy)phenyl)-3-methoxyacrylic Acid (CAS 1185255-09-7)
- 2-Hydrazinylpyrimidine-5-carbonitrile (CAS 38373-51-2)
- 4-Chloro-1-ethyl-1H-pyrazole-3-carbonyl chloride (CAS 1172515-44-4)
- 4-(4-Methylbenzoyl)piperidine hydrochloride (CAS 42060-84-4)
- 4-(5-Methylthiophene-2-carbonyl)morpholine-3-carboxylic acid (CAS 1468506-71-9)
- Methyl (1-hydroxymethylcyclopropyl)acetate (CAS 142148-13-8)
- 2-Amino-4-chloro-N-ethyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzamide (CAS 2415255-63-7)
- Semaglutide impurity 199 (CAS CATO-C4X-2226199)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com