difluoromethyl 4-(4-methylphenyl)-2-pyrimidinyl sulfide CAS 477859-74-8
| CAS No. | 477859-74-8 |
| Molecular Formula | C12H10F2N2S |
| Molecular Weight | 252.28 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), difluoromethyl 4-(4-methylphenyl)-2-pyrimidinyl sulfide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
difluoromethyl 4-(4-methylphenyl)-2-pyrimidinyl sulfide (CAS 477859-74-8) is a high-purity analytical reference standard with the molecular formula C12H10F2N2S and a molecular weight of 252.28 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution, difluoromethyl 4-(4-methylphenyl)-2-pyrimidinyl sulfide is typically pale yellow to yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 252.28 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C12H10F2N2S |
| Molecular Weight | 252.28 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 8.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related difluoromethyl Standards
- 1-(Difluoromethyl)pyrene (CAS 1186195-16-3)
- 1-benzyl-3-(difluoromethyl)-5-ethoxy-1H-pyrazole (CAS 1461706-12-6)
- 4-[(Difluoromethyl)sulfonyl]-1,2-dimethoxybenzene (CAS 1226120-89-3)
- 2-(Difluoromethyl)-4-methoxy-5-methylpyridine-3-sulfonamide (CAS 1805066-23-2)
- 2-(Difluoromethyl)-6-methoxy-4-methylpyridine-3-sulfonamide (CAS 1805066-37-8)
- 2-(Difluoromethyl)-3-methoxy-4-methylpyridine-6-sulfonamide (CAS 1805198-76-8)
- 2-(Difluoromethyl)-4-methoxy-6-methylpyridine-3-sulfonamide (CAS 1805198-92-8)
- 2-(Difluoromethyl)-6-methoxy-3-methylpyridine-4-sulfonamide (CAS 1805199-01-2)
Recommended Standards
- Benzyl N-[trans-3-fluoro-4-piperidyl]carbamate (CAS 577691-96-4)
- Ethyl (1S,2S)-rel-2-(4-ethoxy-3-fluorophenyl)cyclopropane-1-carboxylate (CAS 2055840-77-0)
- Benzyl (3S,4S)-3-(aminomethyl)-4-fluoropyrrolidine-1-carboxylate (CAS 604798-51-8)
- Ethyl 2-(4-ethoxy-3-fluorophenyl)cyclopropane-1-carboxylate (CAS 2001540-59-4)
- Methyl 1-(1-ethoxy-1-oxopropan-2-yl)-1H-pyrazole-3-carboxylate (CAS 1006333-26-1)
- 3-amino-4-(4-ethoxyphenoxy)-N,N-diethylbenzenesulfonamide (CAS 727694-63-5)
- 2-(3-Methoxyphenyl)indolizine (CAS 82682-68-6)
- (S)-(-)-DBD-Pro-COCl[=(S)-(-)-4-(N,N-Dimethylaminosulfonyl)-7-(2-chloroformylpyrrolidin-1-yl)-2,1,3-benzoxadiazole] [HPLC Labeling Reagent for e.e. Determination] (CAS 150993-63-8)
- N-(5-iodo-4-oxo-1,4-dihydropyridin-3-yl)acetamide (CAS 1186311-00-1)
- N-(2,4-difluorophenyl)-3-(trifluoromethyl)benzamide (CAS 860649-44-1)
- 3-(Benzo[d][1,3]dioxol-5-yl)-3-oxopropanenitrile (CAS 96220-14-3)
- 3-(Difluoromethylene)cyclobutan-1-amine hydrochloride (CAS 2688115-06-0)
- Cinacalcet Impurity 29 (CAS 15297-33-3)
- Semaglutide Impurity 133 (CAS CATO-C4X-2226133)
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