3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((tetrahydrofuran-2-yl)methyl)pyridin-2(1H)-one CAS 477860-53-0
| CAS No. | 477860-53-0 |
| Molecular Formula | C17H17ClFNO3 |
| Molecular Weight | 337.77 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((tetrahydrofuran-2-yl)methyl)pyridin-2(1H)-one is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((tetrahydrofuran-2-yl)methyl)pyridin-2(1H)-one (CAS 477860-53-0), molecular formula C17H17ClFNO3 and molecular weight 337.77 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((tetrahydrofuran-2-yl)methyl)pyridin-2(1H)-one (C17H17ClFNO3) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 337.77 g/mol, it falls into the moderately-high-molecular-weight range. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-((tetrahydrofuran-2-yl)methyl)pyridin-2(1H)-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C17H17ClFNO3 |
| Molecular Weight | 337.77 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
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Recommended Standards
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- 2-Methoxy-5-(N-phthalimidinyl)benzenesulfonyl chloride (CAS 126565-42-2)
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- Methyl 4,4-dimethyl-2-[(trifluoromethylsulfonyl)oxy]cyclohex-1-ene-1-carboxylate (CAS 1228780-46-8)
- N-(3-chlorobenzyl)cyclopropanamine (CAS 51586-21-1)
- N-(9-deoxy-epi-cinchonin-9-yl)picolinamide (CAS 1414851-55-0)
- α-Ketobutyric Acid-d (CAS 1007476-82-5)
- N,3-Dimethyl-N-[2-(methylsulfanyl)-4-quinazolinyl]benzenecarbohydrazide (CAS 341968-22-7)
- 1-Allyl-3-bromobenzene (CAS 18257-89-1)
- 1-Ethyl-3-methyl-1H-pyrazole-5-carbonyl isothiocyanate (CAS 1489546-98-6)
- Liraglutide(3-31)TFA Salt (CAS CATO-C4X-19921)
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