3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one CAS 477860-63-2
| CAS No. | 477860-63-2 |
| Molecular Formula | C20H14ClF4NO2 |
| Molecular Weight | 411.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 411.78 g/mol gives 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
CATO supplies 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one (CAS 477860-63-2), a certified reference material (molecular formula C20H14ClF4NO2, MW 411.78 g/mol) for analytical method development and quality control.
Based on its molecular formula C20H14ClF4NO2, 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 411.78 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 3-(2-Chloro-6-fluorobenzyl)-4-hydroxy-1-(3-(trifluoromethyl)benzyl)pyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C20H14ClF4NO2 |
| Molecular Weight | 411.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 1 |
Related Chloro Standards
- (5-Chloro-1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)methyl tosylcarbamate (CAS 282523-54-0)
- Methyl 2-(2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl]sulfanyl}acetyl)-6-oxo-1,2-diazinane-4-carboxylate (CAS 251307-23-0)
- 6-Chloro-7-deaza-9-(2,3,5-tri-O-acetyl-β-D-ribofuranoysyl)purine (CAS 16754-79-3)
- 1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-3-(2-phenoxyethyl)pyrimidine-2,4(1H,3H)-dione (CAS 251310-56-2)
- Methyl 2-{[3-chloro-5-(trifluoromethyl)pyridin-2-yl](methyl)amino}-1-oxo-1,2-dihydroisoquinoline-4-carboxylate (CAS 338793-07-0)
- 2-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-N-[2-(5-methoxy-1H-indol-3-yl)ethyl]acetamide (CAS 866138-31-0)
- 8-[3-Chloro-5-(trifluoromethyl)-2-pyridinyl]-2-phenyl-1,2,4,8-tetraazaspiro[4.5]decan-3-one (CAS 250713-96-3)
- 2-((1-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-1H-imidazol-2-yl)thio)-1-(p-tolyl)ethan-1-one (CAS 303988-47-8)
Recommended Standards
- Butoconazole (CAS 64872-76-0)
- 2-(((4-Bromophenyl)thio)methyl)-4-chloro-6,7-dihydro-5H-cyclopenta[4,5]thieno[2,3-d]pyrimidine (CAS 885459-34-7)
- Butoconazole (CAS 67085-13-6)
- 2-{2-[3-(2H-1,3-benzodioxol-5-yl)-1H-pyrazol-1-yl]ethoxy}-3-chloro-5-(trifluoromethyl)pyridine (CAS 955961-70-3)
- 3'-Cyano-3-methyl-[1,1'-biphenyl]-2-carboxylic acid (CAS 1261945-22-5)
- 2-((Methylamino)oxy)ethanamine (CAS 945674-57-7)
- 2-Methyl-1-(1-methyl-1H-imidazol-2-yl)propan-2-amine (CAS 1393563-45-5)
- 2-Hydroxy-4-(2-{1-[4-(4-methoxyphenyl)-1,3-thiazol-2-yl]-3-methyl-5-oxo-1,5-dihydro-4H-pyrazol-4-ylidene}hydrazino)benzoic acid (CAS 314759-58-5)
- 1'H-spiro[cyclohexane-1,2'-quinazoline]-4'(3'H)-thione (CAS 126492-23-7)
- (2-(Ethyl(methyl)amino)-5-fluoropyridin-4-yl)boronic acid (CAS 2225154-81-2)
- S-(Phenylsulfonyl)-L-cysteine (CAS 97512-83-9)
- 5-Amino-2-(4-aminophenyl)isoindoline-1,3-dione (CAS 13406-77-4)
- 2-(4-Cyanophenyl)-4'-iodoacetophenone (CAS 898784-43-5)
- Semaglutide impurity 250 (CAS CATO-C4X-2226250)
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