7-Chloro-N-(4-fluorobenzyl)quinazolin-4-amine CAS 477861-93-1

Description

Compared with other compounds in its class, the molecular weight of 287.72 g/mol gives 7-Chloro-N-(4-fluorobenzyl)quinazolin-4-amine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

7-Chloro-N-(4-fluorobenzyl)quinazolin-4-amine (CAS 477861-93-1), molecular formula C15H11ClFN3 and molecular weight 287.72 g/mol, is a CATO reference standard with documented purity and traceability.

7-Chloro-N-(4-fluorobenzyl)quinazolin-4-amine (C15H11ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

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