N'-[(1Z)-(4-Chlorophenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide CAS 477864-07-6
| CAS No. | 477864-07-6 |
| Molecular Formula | C18H13ClF6N2O3 |
| Molecular Weight | 454.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N'-[(1Z)-(4-Chlorophenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide (CAS 477864-07-6), molecular formula C18H13ClF6N2O3 and molecular weight 454.75 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, N'-[(1Z)-(4-Chlorophenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 454.75 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), N'-[(1Z)-(4-Chlorophenyl)methylidene]-2,5-bis(2,2,2-trifluoroethoxy)benzohydrazide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H13ClF6N2O3 |
| Molecular Weight | 454.75 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- CCG-1423 (CAS 285986-88-1)
- Tolvaptan Impurity 108 (CAS CATO-C4X-1955108)
- 1-[3-Chloro-5-(trifluoromethyl)pyridin-2-yl]-4-[2-nitro-4-(trifluoromethyl)phenyl]piperazine (CAS 338772-98-8)
- 1-(3,3,5-Trimethylcyclohex-1-en-1-yl)-4-(3-(1-(3,5,5-trimethylcyclohex-1-en-1-yl)piperidin-4-yl)propyl)piperidine (CAS 101012-79-7)
- 2-Fluoro-4-(tributylstannyl)pyrimidine (CAS 1429425-16-0)
- N-(but-2-yn-1-yl)furan-2-carboxamide (CAS 1333470-23-7)
- 4-(4-Bromophenoxy)tetrahydrofuran-3-amine (CAS 1823417-91-9)
- (S)-Ru(OAc)2(H8-BINAP) (CAS 142962-95-6)
- 2,2'-Oxydibenzaldehyde (CAS 49590-51-4)
- 8-Hydroxy-2-(4-nitrophenyl)quinazolin-4(1H)-one (CAS 172462-88-3)
- 1,7,7-Trimethylbicyclo[2.2.1]Heptan-2-yl propionate (CAS 2756-56-1)
- 1-(Difluoromethyl)-5-methoxy-1H-indole (CAS 1599210-06-6)
- 5-Amino-2-(dimethylamino)benzamide (CAS 1226805-88-4)
- Allo-D-Ile12-Tirzepatide (CAS CATO-CPTD788963)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com