(2E)-3-(Furan-2-yl)-N-[4-(trifluoromethyl)phenyl]prop-2-enamide CAS 477867-20-2
| CAS No. | 477867-20-2 |
| Molecular Formula | C14H10F3NO2 |
| Molecular Weight | 281.23 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(2E)-3-(Furan-2-yl)-N-[4-(trifluoromethyl)phenyl]prop-2-enamide (C14H10F3NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
(2E)-3-(Furan-2-yl)-N-[4-(trifluoromethyl)phenyl]prop-2-enamide (CAS 477867-20-2) is a high-purity analytical reference standard with the molecular formula C14H10F3NO2 and a molecular weight of 281.23 g/mol.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10F3NO2 |
| Molecular Weight | 281.23 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep tightly closed to prevent evaporation |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
Related E Standards
- (2E)-3-(Furan-2-yl)-N-[3-(trifluoromethyl)phenyl]prop-2-enamide (CAS 304475-91-0)
- 3-[(furan-2-ylmethyl)sulfamoyl]benzoic acid (CAS 603118-18-9)
- 4-[(furan-2-ylmethyl)sulfamoyl]benzoic acid (CAS 321979-08-2)
- (E)-4-((Furan-2-ylmethylene)amino)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 1164482-67-0)
- 3-Benzyl-1-(furan-2-ylmethyl)-4-hydroxypyridin-2(1H)-one (CAS 478247-65-3)
- 3-(Furan-2-yl)-N-(furan-2-ylmethyl)-3-phenylpropan-1-amine (CAS 396104-71-5)
- 3-(Furan-2-yl)-N-((4-methoxytetrahydro-2H-thiopyran-4-yl)methyl)acrylamide (CAS 2035018-17-6)
- 3-(Furan-2-yl)-N-(2-((tetrahydro-2H-pyran-4-yl)thio)ethyl)acrylamide (CAS 2035000-92-9)
Recommended Standards
- 1-(2-Furylmethyl)-5-(trifluoromethyl)-1H-benzimidazol-2-amine (CAS 878259-07-5)
- 2-(2-(Trifluoromethyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1956334-74-9)
- 1-(4-((5-(Trifluoromethyl)pyridin-2-yl)oxy)phenyl)ethan-1-one (CAS 338978-29-3)
- 2-(3-(Trifluoromethyl)phenyl)-6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one (CAS 1956326-59-2)
- tert-Butyl 4-hydroxy-2-oxo-5,6,8,9-tetrahydro-1H-pyrido[2,3-d]azepine-7(2H)-carboxylate (CAS 959636-64-7)
- 2-(4-Fluorobenzyl)-6,7-dihydro-5H-thiazolo[3,2-a]pyrimidin-3(2H)-one (CAS 1049144-01-5)
- 1-(1,1-Difluoropropyl)-3-(trifluoromethyl)benzene (CAS 1138445-56-3)
- Tert-butyl (3-amino-3-iminopropyl)(methyl)carbamate (CAS 1339718-12-5)
- 7-Chloroquinolin-3-amine (CAS 1195710-15-6)
- 4-(Trifluoromethyl)phenylacetonitrile 4-trifluoromethyl phenylacetonitrile 4-trifluoromethyl phenyl acetonitrile p-trifluoromethylbenzyl cyanide p-trifluoromethylbenzylcyanide 4-trifluoromethylbenzylcyanide 4-(trifluoromethyl)phenyl acetonitrile 4-(Trifluoromethyl)benzyl cyanide 2338-75-2 (CAS 2338-75-2)
- Spiro[azetidine-3,2'-chroman]-4'-one (CAS 1237171-28-6)
- 1-(3-Chloro-4-methylphenyl)pyrimidine-2,4,6(1H,3H,5H)-trione (CAS 879068-92-5)
- 2-((2-Chlorobenzyl)thio)-5-(pyridin-4-yl)-1,3,4-oxadiazole (CAS 478482-74-5)
- Des-Asp15-Tirzepatide (CAS CATO-CPTD788958)
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