4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide CAS 477868-33-0
| CAS No. | 477868-33-0 |
| Molecular Formula | C24H14Cl3F3N2O4S3 |
| Molecular Weight | 653.93 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide (CAS 477868-33-0), molecular formula C24H14Cl3F3N2O4S3 and molecular weight 653.93 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide (C24H14Cl3F3N2O4S3) is characterized by a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-Chloro-N-(2-((3-chloro-5-(trifluoromethyl)pyridin-2-yl)thio)phenyl)-N-((4-chlorophenyl)sulfonyl)benzenesulfonamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C24H14Cl3F3N2O4S3 |
| Molecular Weight | 653.93 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 16.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 3 |
Related Chloro Standards
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Recommended Standards
- [S(R)]-N-[(S)-[3-(Benzyloxy)-2-(dicyclohexylphosphino)phenyl]-(2-naphthalenyl)methyl]-N,2-dimethyl-2-propanesulfinamide (CAS 2565792-55-2)
- Bis[3,5-dibromo-4-(2-hydroxyethoxy)phenyl] Sulfone (CAS 53714-39-9)
- 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecafluoro-1,8-diiodooctane 1,1,2,2,3,3,4,4,5,5,6,6,7,7,8,8-hexadecakis(fluoranyl)-1,8-bis(iodanyl)octane 335-70-6 A821850 (CAS 335-70-6)
- NHC-Pd(II)-Mp catalyst (CAS 1392095-51-0)
- 6-Amino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione (CAS 58481-39-3)
- 4-Methoxy-4-methyl-N-(thiophen-2-ylmethyl)pentan-2-amine (CAS 1092291-86-5)
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- Ethyl (R)-5-hydroxy-2-methyl-1,2,3,6-tetrahydropyridine-4-carboxylate (CAS 2489337-04-2)
- (S)-1-(5-Chloro-2-methoxyphenyl)ethan-1-amine (CAS 1213612-93-1)
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- 5,6,7,8-Tetrahydroimidazo[1,5-a]pyrazin-3-amine dihydrochloride (CAS 165894-32-6)
- Neuropeptide SF (human) (CAS 192387-39-6)
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