(2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide CAS 477870-62-5

Purity 97%+In StockPharmaceutical Standards
CAS No.477870-62-5
Molecular FormulaC12H11Cl2N3O
Molecular Weight284.14 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

(2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide CAS 477870-62-5 chemical structure

Description

Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide.

CATO supplies (2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide (CAS 477870-62-5), a certified reference material (molecular formula C12H11Cl2N3O, MW 284.14 g/mol) for analytical method development and quality control.

The molecular framework of (2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide (C12H11Cl2N3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

As a certified reference material (CRM), (2Z)-2-Cyano-N-(3,5-dichlorophenyl)-3-(dimethylamino)prop-2-enamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

Physical & Chemical Properties

Molecular FormulaC12H11Cl2N3O
Molecular Weight284.14 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light, keep tightly closed to prevent evaporation
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)8.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentCl-containing
Nitrogen Atoms3

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