3-((2-Methylbenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-amine CAS 477872-65-4
| CAS No. | 477872-65-4 |
| Molecular Formula | C14H14N4S2 |
| Molecular Weight | 302.42 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
3-((2-Methylbenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-amine (CAS 477872-65-4) is a high-purity analytical reference standard with the molecular formula C14H14N4S2 and a molecular weight of 302.42 g/mol.
3-((2-Methylbenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-amine (C14H14N4S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. Its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C14H14N4S2 |
| Molecular Weight | 302.42 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Methylbenzyl Standards
- 3-((4-Methylbenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazol-4-amine (CAS 477857-63-9)
- 3-Methyl-2-((3-methylbenzyl)thio)thieno[3,2-d]pyrimidin-4(3H)-one (CAS 923702-77-6)
- 2-(2-Methylbenzyl)-2H-benzo[e][1,2,4]thiadiazin-3(4H)-one 1,1-dioxide (CAS 1021227-19-9)
- 1-(4-Methylbenzyl)-1H-benzo[d]imidazole-2-sulfonic acid (CAS 537010-03-0)
- 2-((4-Methylbenzyl)amino)-2-oxoethyl 3-methylthiophene-2-carboxylate (CAS 733013-19-9)
- 5-(3-((4-Methylbenzyl)oxy)thiophen-2-yl)-1,2-dihydro-3H-1,2,4-triazole-3-thione (CAS 343376-08-9)
- N1-(4-Methylbenzyl)-N2-((1-methylpiperidin-4-yl)methyl)oxalamide (CAS 953171-33-0)
- 4-Methyl-3-((2-methylbenzyl)thio)-5-(thiophen-2-yl)-4H-1,2,4-triazole (CAS 294848-72-9)
Recommended Standards
- 1-Benzyl-4,6-bis(methylthio)-1H-pyrazolo[3,4-d]pyrimidine (CAS 126867-57-0)
- 4-(piperazin-1-yl)-2,6-di-(pyrrolÂidin-1-yl)-pyrimidine (CAS 111641-17-9)
- 4-Ethyl-5-(4-methyl-2-phenyl-1,3-thiazol-5-yl)-4H-1,2,4-triazol-3-ylhydrosulfide (CAS 219860-19-2)
- Methothrin (CAS 34388-29-9)
- 4-(3-(3,5-Dibromophenyl)-2,5-dioxopyrrolidin-1-yl)benzenesulfonamide (CAS 93553-57-2)
- Ethyl 8-chloro-2-methylimidazo[1,2-a]pyrazine-3-carboxylate (CAS 1656281-16-1)
- 4,6-Dibromo-2,3-difluorophenylacetonitrile (CAS 1804939-10-3)
- 1-(5-(3-Aminopyrrolidine-1-carbonyl)thiophen-2-yl)ethan-1-one (CAS 2098101-12-1)
- 2-(4-(Methylsulfonyl)piperazin-1-yl)phenol (CAS 1221792-82-0)
- 1-(4-Chloro-2-methoxybenzyl)pyrrolidin-3-amine (CAS 1707746-69-7)
- 4-Amino-6-bromoisochromane Hydrochloride (CAS 676134-73-9)
- Methyl 2-(5-fluoro-2-oxo-1,2-dihydropyridin-4-yl)propanoate (CAS 2755892-94-3)
- Ethyl 5-amino-4-bromo-1-(pentan-3-yl)-1H-pyrazole-3-carboxylate (CAS 1427024-25-6)
- Semaglutide Impurity 155 (x TFA Salt) (CAS CATO-C4X-2226155)
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