4-(Morpholin-4-yl)-2-(pyridin-2-yl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile CAS 477872-96-1
| CAS No. | 477872-96-1 |
| Molecular Formula | C21H16F3N5O |
| Molecular Weight | 411.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 4-(Morpholin-4-yl)-2-(pyridin-2-yl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile (C21H16F3N5O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
4-(Morpholin-4-yl)-2-(pyridin-2-yl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile (CAS 477872-96-1) is a high-purity analytical reference standard with the molecular formula C21H16F3N5O and a molecular weight of 411.38 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 4-(Morpholin-4-yl)-2-(pyridin-2-yl)-6-[3-(trifluoromethyl)phenyl]pyrimidine-5-carbonitrile under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H16F3N5O |
| Molecular Weight | 411.38 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 5 |
Related Morpholin Standards
- N-[3-(Morpholin-4-yl)propyl]-4-[3-(trifluoromethyl)benzoyl]-1H-pyrrole-2-carboxamide (CAS 439111-17-8)
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Recommended Standards
- 2-(2-((4-Bromobenzyl)thio)thiazol-4-yl)-N-cyclopentylacetamide (CAS 954069-97-7)
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- 3-((4-Nitro-1h-pyrazol-1-yl)methyl)benzoic acid (CAS 514801-16-2)
- 2-(((2-Morpholinopyrimidin-5-yl)methyl)amino)acetic acid (CAS 1279207-02-1)
- 1-(2,6-Dichlorobenzyl)-3,5-diphenyl-1H-1,2,4-triazole (CAS 332916-09-3)
- N-Methyl-(R)-1-ferrocenyl-(S)-(2-diphenylphosphino)ethylamin (CAS 778511-13-0)
- Peptide Impurity 64 (CAS CATO-CPTD788964)
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