1-Methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide CAS 477886-35-4
| CAS No. | 477886-35-4 |
| Molecular Formula | C15H9F6N3OS |
| Molecular Weight | 393.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-Methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide.
1-Methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide (CAS 477886-35-4), molecular formula C15H9F6N3OS and molecular weight 393.31 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 1-Methyl-3-(trifluoromethyl)-N-(3-(trifluoromethyl)phenyl)-1H-thieno[2,3-c]pyrazole-5-carboxamide (C15H9F6N3OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C15H9F6N3OS |
| Molecular Weight | 393.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Methyl Standards
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Recommended Standards
- 1-(4-(2,4-Dichlorophenyl)thiazol-2-yl)-4-(thiophen-2-yl)-1H-pyrazol-5-amine (CAS 955965-57-8)
- 2-Methylthioadenosine 5-monophosphate (CAS 22140-20-1)
- (E)-2-(2,4-dichlorostyryl)-1-(4-methylbenzyl)-1H-benzo[d]imidazole (CAS 321433-12-9)
- Betamethasone Impurity 136 (CAS CATO-C4X-1437136)
- 3-(4-Chlorophenyl)-2-(4-methylbenzenesulfonamido)propanoic acid (CAS 203306-45-0)
- 4-Chloro-2-fluoro-3-methoxybenzamide (CAS 1323966-12-6)
- 3,5-Dichloro-2-fluorobenzodifluoride (CAS 1804514-43-9)
- 2,8-Dimethylquinoline-6-carboxylic acid (CAS 1368259-21-5)
- 5-Methanesulfonyl-4H,6H,7H-thieno[3,2-c]pyridine (CAS 1343171-46-9)
- 2-(Quinolin-4-ylthio)acetohydrazide (CAS 885278-19-3)
- Ethyl 4,6-dihydroxy-5-iodonicotinate (CAS 1353878-12-2)
- 6-Bromo-4-chloro-2-methyl-2H-indazole (CAS 1976003-92-5)
- N-((2-morpholinopyrimidin-5-yl)methyl)propan-2-amine (CAS 1273999-33-9)
- C-Type Natriuretic Peptide (32-53) (human, porcine, rat) (CAS 127869-51-6)
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