8-Methyl-N-(4-(trifluoromethoxy)phenyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide CAS 477887-29-9
| CAS No. | 477887-29-9 |
| Molecular Formula | C20H14F3NO2S2 |
| Molecular Weight | 421.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
As a certified reference material (CRM), 8-Methyl-N-(4-(trifluoromethoxy)phenyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
8-Methyl-N-(4-(trifluoromethoxy)phenyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide (CAS 477887-29-9) is a high-purity analytical reference standard with the molecular formula C20H14F3NO2S2 and a molecular weight of 421.46 g/mol.
The molecular framework of 8-Methyl-N-(4-(trifluoromethoxy)phenyl)-4H-thieno[3,2-c]thiochromene-2-carboxamide (C20H14F3NO2S2) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C20H14F3NO2S2 |
| Molecular Weight | 421.46 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Recommended Standards
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