3-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole CAS 477887-90-4

Purity 97%+In StockPharmaceutical Standards
CAS No.477887-90-4
Molecular FormulaC24H20F3N3S2
Molecular Weight471.56 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

3-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole CAS 477887-90-4 chemical structure

Description

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

3-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole (CAS 477887-90-4) is a high-purity analytical reference standard with the molecular formula C24H20F3N3S2 and a molecular weight of 471.56 g/mol.

The molecular framework of 3-(4,5-Dihydronaphtho[1,2-b]thiophen-2-yl)-4-ethyl-5-((3-(trifluoromethyl)benzyl)thio)-4H-1,2,4-triazole (C24H20F3N3S2) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

Molecular FormulaC24H20F3N3S2
Molecular Weight471.56 g/mol
Purity97%+
StorageStore at room temperature, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)15.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF-containing
Nitrogen Atoms3
Sulfur Atoms2

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