Methyl (Z)-3-(4-chloroanilino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-propenoate CAS 477888-03-2
| CAS No. | 477888-03-2 |
| Molecular Formula | C16H11Cl2F3N2O2 |
| Molecular Weight | 391.17 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Methyl (Z)-3-(4-chloroanilino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-propenoate (CAS 477888-03-2), molecular formula C16H11Cl2F3N2O2 and molecular weight 391.17 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of Methyl (Z)-3-(4-chloroanilino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-propenoate (C16H11Cl2F3N2O2) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures Methyl (Z)-3-(4-chloroanilino)-2-[3-chloro-5-(trifluoromethyl)-2-pyridinyl]-2-propenoate under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H11Cl2F3N2O2 |
| Molecular Weight | 391.17 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Recommended Standards
- (3-Acetoxy-5-(5-bromo-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)tetrahydrofuran-2-yl)methyl acetate (CAS 6161-23-5)
- 2-(2,6-Dichloro-4-(3,5-dioxo-4,5-dihydro-1,2,4-triazin-2(3H)-yl)phenyl)-2-(4-fluorophenyl)acetonitrile (CAS 103337-74-2)
- n-(4-Iodophenyl)-2-oxo-2h-chromene-3-carboxamide (CAS 92792-09-1)
- tributyl(2-phenylethynyl)stannane (CAS 3757-88-8)
- Sodium 4-((perfluorohex-1-en-1-yl)oxy)benzenesulfonate (CAS 59493-84-4)
- (1-Isopropyl-1H-benzo[d]imidazol-2-yl)methanamine dihydrochloride (CAS 1334146-16-5)
- 2-Bromo-6-(difluoromethyl)-4-nitropyridine-3-sulfonamide (CAS 1804433-57-5)
- 2-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]-3-methoxy-benzaldehyde (CAS 126357-82-2)
- 2-(3-Chloropyridin-4-yl)ethanethioamide (CAS 1478862-75-7)
- Cyclopropyl(3,4-dimethylphenyl)methanamine (CAS 535925-77-0)
- Hybutimibe Impurity 5 (CAS CATO-C4X-25055)
- 8-Chloro-4-iodoisoquinolin-3-amine (CAS 2234239-94-0)
- 6-[(Z)-2-ethoxyethenyl]pyrrolo[2,1-f][1,2,4]triazin-4-amine (CAS 1253962-45-6)
- Semaglutide impurity 29 (CAS CATO-C4X-222629)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com