5-Iodo-N-(3-methoxypropyl)-2,6-dimethylpyrimidin-4-amine CAS 477888-24-7

Purity 97%+In StockPharmaceutical Standards
CAS No.477888-24-7
Molecular FormulaC10H16IN3O
Molecular Weight321.16 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

5-Iodo-N-(3-methoxypropyl)-2,6-dimethylpyrimidin-4-amine CAS 477888-24-7 chemical structure

Description

The occurrence of 5-Iodo-N-(3-methoxypropyl)-2,6-dimethylpyrimidin-4-amine is closely related to a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

5-Iodo-N-(3-methoxypropyl)-2,6-dimethylpyrimidin-4-amine (CAS 477888-24-7) is a high-purity analytical reference standard with the molecular formula C10H16IN3O and a molecular weight of 321.16 g/mol.

The molecular framework of 5-Iodo-N-(3-methoxypropyl)-2,6-dimethylpyrimidin-4-amine (C10H16IN3O) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, iodine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC10H16IN3O
Molecular Weight321.16 g/mol
AppearanceOff-white to pale yellow crystalline powder. (slight halide-like odor, faint amine-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)4.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentI-containing
Nitrogen Atoms3

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