N-(2-Methylphenyl)-2-{4-[4-(thiophen-2-yl)pyrimidin-2-yl]phenoxy}acetamide CAS 477888-35-0

Purity 97%+In StockPharmaceutical Standards
CAS No.477888-35-0
Molecular FormulaC23H19N3O2S
Molecular Weight401.48 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-(2-Methylphenyl)-2-{4-[4-(thiophen-2-yl)pyrimidin-2-yl]phenoxy}acetamide CAS 477888-35-0 chemical structure

Description

The occurrence of N-(2-Methylphenyl)-2-{4-[4-(thiophen-2-yl)pyrimidin-2-yl]phenoxy}acetamide is closely related to a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.

N-(2-Methylphenyl)-2-{4-[4-(thiophen-2-yl)pyrimidin-2-yl]phenoxy}acetamide (CAS 477888-35-0), molecular formula C23H19N3O2S and molecular weight 401.48 g/mol, is a CATO reference standard with documented purity and traceability.

N-(2-Methylphenyl)-2-{4-[4-(thiophen-2-yl)pyrimidin-2-yl]phenoxy}acetamide (C23H19N3O2S) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. It is notably hygroscopic, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC23H19N3O2S
Molecular Weight401.48 g/mol
Purity97%+
StorageStore in a cool place (≤25°C), protect from light, keep sealed and dry
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening
Degree of Unsaturation (DBE)16.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Nitrogen Atoms3
Sulfur Atoms1

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