7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 477888-44-1

Purity 97%+In StockPharmaceutical Standards
CAS No.477888-44-1
Molecular FormulaC18H12ClFN4O
Molecular Weight354.77 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine CAS 477888-44-1 chemical structure

Description

Compared with other compounds in its class, the molecular weight of 354.77 g/mol gives 7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine distinctive chromatographic separation conditions and mass-spectrometry parameter settings.

CATO supplies 7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (CAS 477888-44-1), a certified reference material (molecular formula C18H12ClFN4O, MW 354.77 g/mol) for analytical method development and quality control.

The molecular framework of 7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine (C18H12ClFN4O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

CATO manufactures 7-(4-((2-Chloro-6-fluorobenzyl)oxy)phenyl)-[1,2,4]triazolo[1,5-a]pyrimidine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.

Physical & Chemical Properties

Molecular FormulaC18H12ClFN4O
Molecular Weight354.77 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor, low volatility)
Purity97%+
StorageStore at 2-8°C, protect from light
Solubility (reference)Soluble in DMSO, DMF, methanol
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light
Degree of Unsaturation (DBE)14.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentF/Cl-containing
Nitrogen Atoms4

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