(E)-3-(((4-chlorobenzyl)oxy)imino)-2-(4-(3-fluoropropoxy)phenyl)propanenitrile CAS 477889-17-1
| CAS No. | 477889-17-1 |
| Molecular Formula | C19H18ClFN2O2 |
| Molecular Weight | 360.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-3-(((4-chlorobenzyl)oxy)imino)-2-(4-(3-fluoropropoxy)phenyl)propanenitrile.
CATO supplies (E)-3-(((4-chlorobenzyl)oxy)imino)-2-(4-(3-fluoropropoxy)phenyl)propanenitrile (CAS 477889-17-1), a certified reference material (molecular formula C19H18ClFN2O2, MW 360.81 g/mol) for analytical method development and quality control.
(E)-3-(((4-chlorobenzyl)oxy)imino)-2-(4-(3-fluoropropoxy)phenyl)propanenitrile (C19H18ClFN2O2) contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H18ClFN2O2 |
| Molecular Weight | 360.81 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related E Standards
- N-(2-Chlorobenzyl)-2-((5-(pyridin-4-yl)-1,3,4-oxadiazol-2-yl)thio)acetamide (CAS 721406-24-2)
- 3-(4-Chlorobenzyl)-1-(furan-3-ylmethyl)-1-(thiophen-2-ylmethyl)urea (CAS 1421507-68-7)
- 1-(4-Chlorobenzyl)-3-(4-ethyl-5-(methylthio)-4H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 400075-00-5)
- 2-((4-Chlorobenzyl)thio)-N-(2,3-dichlorophenyl)acetamide (CAS 306732-07-0)
- 1-(3-Chlorobenzyl)-3-(4-chlorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 477846-46-1)
- 2-((4-Chlorobenzyl)thio)-N-(2-methoxyethyl)quinazolin-4-amine (CAS 422532-96-5)
- Ethyl 4-(2-chlorobenzyl)-3-methyl-4H-benzo[b][1,4]thiazine-2-carboxylate (CAS 339098-19-0)
- 1-(4-Chlorobenzyl)-4-(3-(thiophen-2-yl)-1,2,4-oxadiazol-5-yl)pyrrolidin-2-one (CAS 1105244-01-6)
Recommended Standards
- 1-(2-Chlorophenyl)-3-((5-(furan-2-carbonyl)thiophen-2-yl)methyl)urea (CAS 1798022-45-3)
- 2-Chloro-1-(4-((2,3-dihydrobenzo[b][1,4]dioxin-6-yl)sulfonyl)piperazin-1-yl)ethan-1-one (CAS 722491-28-3)
- 5-(2-Aminothiazol-4-yl)-2-((4-chlorobenzyl)oxy)benzoic acid (CAS 1416347-30-2)
- 2-Chloro-5-(N-(3-(2-oxopyrrolidin-1-yl)propyl)sulfamoyl)benzoic acid (CAS 380426-71-1)
- Ethyl 2-(2-bromo-3-cyano-4-(trifluoromethyl)phenyl)acetate (CAS 1805187-87-4)
- Cobalt,bis(D-gluconato-κO1,κO2)-,hydrate (1:?),(T-4)- (CAS 1809162-99-9)
- 5-(Pyrrolidin-1-yl)-1,2,3,4-thiatriazole (CAS 500213-98-9)
- 3-Methyl-N-(pyridin-3-ylmethyl)aniline (CAS 1019512-90-3)
- 4-Chloro-7-iodo-2-(methylthio)pyrrolo[2,1-f][1,2,4]triazine (CAS 1824080-03-6)
- 4-Hydroxy-6-methyl-1-(pyridin-2-ylmethyl)pyridin-2(1H)-one (CAS 586378-69-0)
- 4-(Bromomethyl)-1,3,5-trimethyl-1h-pyrazole hydrobromide (CAS 2089257-43-0)
- 4-(4-Methoxy-phenyl)-piperidine hydrochloride 4-(4-methoxyphenyl)piperidine hydrochloride 6748-48-7 (CAS 6748-48-7)
- 3-Oxo-7-(trifluoromethyl)isoindoline-5-carbaldehyde (CAS 2368850-10-4)
- Semaglutide Impurity 129 (CAS 2490269-79-7)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com