N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide CAS 477889-92-2
| CAS No. | 477889-92-2 |
| Molecular Formula | C14H10F3IN2O |
| Molecular Weight | 406.14 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide (CAS 477889-92-2), molecular formula C14H10F3IN2O and molecular weight 406.14 g/mol, is a CATO reference standard with documented purity and traceability.
N-(5-iodo-3-methylpyridin-2-yl)-4-(trifluoromethyl)benzamide (C14H10F3IN2O) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, fluorine/iodine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C14H10F3IN2O |
| Molecular Weight | 406.14 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/I-containing |
| Nitrogen Atoms | 2 |
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- Bromo-3-thienyl-magnesium (CAS 106032-16-0)
- 2,3,6-Trifluorophenylmethylsulfone (CAS 236739-04-1)
- (S)-Benzyl (1-(2-aminoacetyl)pyrrolidin-3-yl)(methyl)carbamate (CAS 1354016-41-3)
- Isopropyl 4-(4-nitrophenyl)butanoate (CAS 94086-76-7)
- cis-2-methylcyclopropanecarboxylic acid (CAS 6142-57-0)
- 2-((3-Chloropyrazin-2-yl)(2-phenylquinolin-7-yl)methyl)isoindoline-1,3-dione (CAS 867162-39-8)
- (3-(1,3-Dioxolan-2-yl)phenyl)(cyclopropyl)methanone (CAS 898759-72-3)
- Semaglutide238 (CAS CATO-C4X-2226238)
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