N,2-Bis[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxamide CAS 478030-48-7

Description

As a certified reference material (CRM), N,2-Bis[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.

N,2-Bis[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxamide (CAS 478030-48-7), molecular formula C18H14Cl2N2OS and molecular weight 377.29 g/mol, is a CATO reference standard with documented purity and traceability.

The molecular framework of N,2-Bis[(4-chlorophenyl)methyl]-1,3-thiazole-4-carboxamide (C18H14Cl2N2OS) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

Physical & Chemical Properties

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