(E)-1-((4-chlorophenyl)sulfonyl)-N'-(4-hydroxy-3-methoxybenzylidene)piperidine-4-carbohydrazide CAS 478030-79-4
| CAS No. | 478030-79-4 |
| Molecular Formula | C20H22ClN3O5S |
| Molecular Weight | 451.92 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
CATO supplies (E)-1-((4-chlorophenyl)sulfonyl)-N'-(4-hydroxy-3-methoxybenzylidene)piperidine-4-carbohydrazide (CAS 478030-79-4), a certified reference material (molecular formula C20H22ClN3O5S, MW 451.92 g/mol) for analytical method development and quality control.
(E)-1-((4-chlorophenyl)sulfonyl)-N'-(4-hydroxy-3-methoxybenzylidene)piperidine-4-carbohydrazide (C20H22ClN3O5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution. It is notably hygroscopic, halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
Physical & Chemical Properties
| Molecular Formula | C20H22ClN3O5S |
| Molecular Weight | 451.92 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 11.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related E Standards
- Benzyl 2-((2-((4-chlorophenyl)amino)-2-oxoethyl)thio)-1H-benzo[d]imidazole-1-carboxylate (CAS 847231-83-8)
- Ethyl 1-[(4-chlorophenyl)methyl]-4-(4-methoxybenzenesulfonyl)piperidine-4-carboxylate (CAS 866135-91-3)
- 4-(4-(4-Chlorophenyl)-2-(propan-2-ylidenehydrazono)thiazol-3(2H)-yl)-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one (CAS 402946-48-9)
- N-(4-chlorophenyl)-4-(1-methyl-6-(methylamino)-3,5-dinitro-1,4-dihydropyridin-2-yl)piperazine-1-carboxamide (CAS 339020-75-6)
- 3-(4-Chlorophenyl)-5-(methylthio)-N-(4-phenoxyphenyl)thiophene-2-carboxamide (CAS 477857-99-1)
- 5-[(4-Chlorophenyl)sulfanyl]-4-phenyl-2-[5-(thiophen-2-yl)-1H-pyrazol-1-yl]-1,3-thiazole (CAS 956372-19-3)
- 4-(4-Chlorophenyl)-1-[3-[2-(4-Fluorophenyl)-1,3-Dithiolan-2-Yl]Propyl]Piperidin-4-Ol (CAS 150176-80-0)
- 5-(4-Chlorophenyl)-4-(3-iodophenyl)-1,2-dimethylpyrrole-3-carboxylic Acid (CAS 1305320-66-4)
Recommended Standards
- Sch 58053 (CAS 194423-53-5)
- (R)-5-Chloro-N-(3-methoxy-1-((3-methyl-4-(3-oxomorpholino)phenyl)amino)-1-oxopropan-2-yl)thiophene-2-carboxamide (CAS 811811-33-3)
- Norcisapride (CAS 102671-04-5)
- 4-Chloronaphthalen-1-yl 2-(N-phenylbenzenesulfonamido)acetate (CAS 343373-65-9)
- 4-Bromo-N-(4,5-dimethylthiazol-2-yl)-1-methyl-1H-pyrrole-2-carboxamide (CAS 923828-89-1)
- (3-((1,4-Dioxa-8-azaspiro[4.5]Decan-8-yl)methyl)phenyl)(2-fluorophenyl)methanone (CAS 898762-01-1)
- 2,6-Dibromodithieno[3,2-b:2 inverted exclamation marka,3 inverted exclamation marka-d]thiophene 67061-69-2 (CAS 67061-69-2)
- Fmoc-3-(4-Quinolyl)-D-Ala-OH (CAS 1997440-75-1)
- 2,2'-((2-((2-((carboxymethyl)amino)ethyl)amino)ethyl)azanediyl)diacetic acid (CAS 762191-10-6)
- 3-Bromo-2-fluoro-6-iodobenzoic acid (CAS 217816-54-1)
- 3-chloro-2-(propane-2-sulfonyl)aniline (CAS 1097921-24-8)
- 2,4-Dichloro-1-{[({2-[(4-chlorophenyl)sulfanyl]phenyl}methyl)sulfanyl]methyl}benzene (CAS 337923-79-2)
- 2-((3-Amino-4-nitrophenyl)amino)ethan-1-ol (CAS 111861-02-0)
- Semaglutide Impurity 166 (CAS 1395881-03-4)
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