4-[3-(Trifluoromethyl)phenoxy]pyrrolo[1,2-a]quinoxaline CAS 478032-24-5
| CAS No. | 478032-24-5 |
| Molecular Formula | C18H11F3N2O |
| Molecular Weight | 328.29 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The occurrence of 4-[3-(Trifluoromethyl)phenoxy]pyrrolo[1,2-a]quinoxaline is closely related to a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution in its molecular formula, which determines its behaviour during synthesis, purification, or degradation.
4-[3-(Trifluoromethyl)phenoxy]pyrrolo[1,2-a]quinoxaline (CAS 478032-24-5), molecular formula C18H11F3N2O and molecular weight 328.29 g/mol, is a CATO reference standard with documented purity and traceability.
The molecular framework of 4-[3-(Trifluoromethyl)phenoxy]pyrrolo[1,2-a]quinoxaline (C18H11F3N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
CATO manufactures 4-[3-(Trifluoromethyl)phenoxy]pyrrolo[1,2-a]quinoxaline under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H11F3N2O |
| Molecular Weight | 328.29 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 2 |
Related Trifluoromethyl Standards
- 1-Phenyl-3-(trifluoromethyl)-1H-pyrazolo[3,4-b]quinolin-6-amine (CAS 1416374-54-3)
- (2E)-2-({[4-(trifluoromethyl)phenyl]amino}methylidene)-hexahydropyrrolo[2,1-b][1,3]thiazole-3,5-dione (CAS 338960-08-0)
- 2-{[4-Phenyl-6-(trifluoromethyl)pyrimidin-2-yl]-thio}propanoic acid (CAS 505054-76-2)
- 1-((1-(2-(Trifluoromethyl)pyrimidin-4-yl)piperidin-4-yl)methyl)pyrrolidin-2-one (CAS 123259-91-6)
- 6-((3-(Trifluoromethyl)phenyl)thio)imidazo[2,1-b]thiazole-5-carbaldehyde (CAS 175277-56-2)
- (7-(Trifluoromethyl)benzo[b]thiophen-2-yl)boronic acid (CAS 936901-97-2)
- 3-[3-(trifluoromethyl)phenyl]-1,2-thiazole-4-sulfonyl chloride (CAS 1909337-34-3)
- 7-Methyl-2-(4-(trifluoromethyl)phenyl)-5H-[1,3,4]thiadiazolo[3,2-a]pyrimidine-5-thione (CAS 866142-89-4)
Recommended Standards
- 3-Methyl-6-(naphthalen-2-yl)-4-(trifluoromethyl)isoxazolo[5,4-b]pyridine (CAS 853312-75-1)
- 6-Methyl-2-(naphthalen-2-yloxy)-4-(trifluoromethyl)pyridine-3-carbonitrile (CAS 478049-81-9)
- 3-(P-tolyl)-5-(trifluoromethyl)-[1,2,4]triazolo[4,3-c]quinazoline (CAS 303148-62-1)
- 7,7'-(Ethane-1,2-diyl)bis(2-amino-1H-purin-6(7H)-one) (CAS 72409-55-3)
- (3-(1-Propyl-1H-pyrazol-5-yl)-1,2,4-oxadiazol-5-yl)methanamine (CAS 1710302-25-2)
- 3-(methoxymethyl)pyrrolidine-1-carbonyl chloride (CAS 1541965-20-1)
- 4-Isothiazolecarbonitrile, 2,3-dihydro-5-mercapto-3-thioxo-, disodium salt (CAS 2076-67-7)
- 1-Sulfamoylpiperidine-3-carboxylic acid (CAS 1016784-46-5)
- Salicylic Acid Mix 5 (CAS CATO-MCHM702009-ME)
- 4,6-Dimethylisobenzofuran-1,3-dione (CAS 60398-94-9)
- 1-Ethoxy-4-(prop-2-yn-1-yloxy)benzene (CAS 5651-84-3)
- 1-(4-Ethylphenyl)-2,2,2-trifluoroethanol (CAS 131252-25-0)
- 4-(2-Chloroethyl)-1,1-dimethylpiperazin-1-ium chloride (CAS 108129-20-0)
- Semaglutide Impurity 192 (CAS CATO-C4X-2226192)
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