1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one CAS 478032-26-7
| CAS No. | 478032-26-7 |
| Molecular Formula | C22H20F3NO5S |
| Molecular Weight | 467.46 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one.
1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one (CAS 478032-26-7) is a high-purity analytical reference standard with the molecular formula C22H20F3NO5S and a molecular weight of 467.46 g/mol.
1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one (C22H20F3NO5S) contains a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. Halogen substitution raises its density and boiling point, the carboxyl group imparts weak acidity; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(1-(2,5-Dimethoxyphenyl)-2-methyl-5-(4-(methylsulfonyl)phenyl)-1H-pyrrol-3-yl)-2,2,2-trifluoroethan-1-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H20F3NO5S |
| Molecular Weight | 467.46 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in methanol, acetonitrile, DMSO, water (slightly soluble) |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 1 |
Related Dimethoxyphenyl Standards
- N-(3,5-dimethoxyphenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040632-91-4)
- N-(3,4-dimethoxyphenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1040682-06-1)
- N-(2,4-dimethoxyphenyl)-2-((3-methyl-4-oxo-7-phenyl-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)thio)acetamide (CAS 1111418-36-0)
- 2'-(3,4-Dimethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole (CAS 188860-26-6)
- 5-((3-(3,4-Dimethoxyphenyl)-1-phenyl-1H-pyrazol-4-yl)methylene)-3-isopropyl-2-thioxothiazolidin-4-one (CAS 623935-77-3)
- 3-(3,4-Dimethoxyphenyl)-1H-1,2,4-triazole-5(4H)-thione (CAS 5585-67-1)
- N-(2,4-Dimethoxyphenyl)-2-((5-((4-methoxybenzyl)thio)-1,3,4-thiadiazol-2-yl)thio)acetamide (CAS 577999-56-5)
- 6-((3-(3,4-Dimethoxyphenyl)-1,2,4-oxadiazol-5-yl)methyl)-3-(3-fluorobenzyl)-3,6-dihydro-7H-[1,2,3]triazolo[4,5-d]pyrimidin-7-one (CAS 1040639-91-5)
Recommended Standards
- (S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)(methyl)amino)-3-(4-(difluoromethoxy)phenyl)propanoic acid (CAS 2255321-53-8)
- N-(3-(((2-((4-Hydroxyphenyl)amino)-5-(trifluoromethyl)pyrimidin-4-yl)amino)methyl)phenyl)-N-methylmethanesulfonamide (CAS 2296719-34-9)
- Nickel(II) Dibutyldithiocarbamate (CAS 13927-77-0)
- MC-PEG2-C2-NHS ester (CAS 1263044-56-9)
- 2-(Trifluoromethyl)-6-(3,3,3-trifluoropropoxy)pyridine 1779122-58-5 (CAS 1779122-58-5)
- tert-butyl 4-[4-nitro-2-(trifluoromethyl)phenyl]piperazine-1-carboxylate (CAS 193902-86-2)
- 2-(Bromomethyl)-1-chloro-3-fluoro-4-methylbenzene (CAS 261762-88-3)
- Tert-butyl 5-(benzyloxy)-3-formyl-1H-indole-1-carboxylate (CAS 914348-98-4)
- N-ethyl-N-methyl-2-(piperidin-4-yloxy)acetamide (CAS 902836-87-7)
- 2-[(2-amino-4-methyl-1,3-thiazol-5-yl)sulfanyl]acetamide (CAS 1000933-46-9)
- 5-Bromo-2-(cyclopropylmethoxy)pyridine (CAS 494772-02-0)
- 7-Iodo-2-methyloxazolo[4,5-c]pyridine (CAS 1823338-99-3)
- n-(4-Fluorophenyl)-5-methyl-3-phenylisoxazole-4-carboxamide (CAS 505088-42-6)
- Insulin Glargine (CAS 160337-95-1)
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