478039-21-3 5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione KS-000036HG CAS 478039-21-3
| CAS No. | 478039-21-3 |
| Molecular Formula | C19H14ClFN2O4 |
| Molecular Weight | 388.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 478039-21-3 5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione KS-000036HG.
478039-21-3 5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione KS-000036HG (CAS 478039-21-3), molecular formula C19H14ClFN2O4 and molecular weight 388.78 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a hydroxyl group, an ether linkage, fluorine/chlorine substitution, 478039-21-3 5-{[2-(4-chloro-3-fluorophenoxy)phenyl]methylene}-1,3-dimethyl-2,4,6(1H,3H,5H)-pyrimidinetrione KS-000036HG is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 388.78 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C19H14ClFN2O4 |
| Molecular Weight | 388.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 2 |
Related chloro Standards
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- 2-{[(2-chloro-6-fluorophenyl)methyl]sulfanyl}-5-[4-(trifluoromethyl)phenyl]-1,3,4-oxadiazole (CAS 477857-20-8)
- (S)-2-(6-(2-Chloro-4-(trifluoromethyl)phenoxy)-2,3-dihydrobenzo[b]thiophen-3-yl)acetic acid (CAS 1022979-27-6)
- (R)-2-(6-(2-Chloro-4-(trifluoromethyl)phenoxy)-2,3-dihydrobenzo[b]thiophen-3-yl)acetic acid (CAS 1022979-28-7)
- 4-(3-Chloro-5-(trifluoromethyl)pyridin-2-yl)-4-(phenylsulfonyl)butanenitrile (CAS 338406-76-1)
- 4-(2-(2-Chloro-4-nitrophenoxy)acetamido)benzene-1-sulfonyl fluoride (CAS 21278-51-3)
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Recommended Standards
- Afatinib Impurity 90 (CAS CATO-C4X-100690)
- 6-(4-Chlorophenyl)-2-oxo-1-(4-(trifluoromethyl)benzyl)-1,2-dihydropyridine-3-carbonitrile (CAS 339109-58-9)
- Tedizolid Impurity 31 (CAS 1239662-46-4)
- 5-(4-Chlorophenyl)-2-oxo-1-{[3-(trifluoromethyl)phenyl]methyl}-1,2-dihydropyridine-3-carbonitrile (CAS 338954-80-6)
- 2-((Tetrahydrofuran-3-yl)oxy)acetic acid (CAS 766539-53-1)
- N'-(2-Chloro-4-methylphenyl)quinoline-4-carbohydrazide (CAS 918296-20-5)
- Tert-butyl (9-oxobicyclo[3.3.1]Nonan-3-yl)carbamate (CAS 1781342-95-7)
- Voriconazole Impurity 75 (CAS 321588-94-7)
- tert-Butyl 4-amino-4-(2-fluorophenyl)piperidine-1-carboxylate (CAS 1707369-76-3)
- N1-(Isoxazol-3-yl)-N2-((tetrahydrofuran-2-yl)methyl)oxalamide (CAS 899978-27-9)
- Muscarine (CAS 300-54-9)
- 6-Bromo-1-propylcinnolin-4(1H)-one (CAS 61588-18-9)
- 2-Bromo-3-(difluoromethyl)-6-fluoro-4-iodopyridine (CAS 1806051-83-1)
- Semaglutide Impurity 188 (CAS CATO-C4X-2226188)
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