2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(pyridin-2-ylmethyl)propanamide CAS 478040-54-9
| CAS No. | 478040-54-9 |
| Molecular Formula | C21H24N4O3S |
| Molecular Weight | 412.51 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO supplies 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(pyridin-2-ylmethyl)propanamide (CAS 478040-54-9), a certified reference material (molecular formula C21H24N4O3S, MW 412.51 g/mol) for analytical method development and quality control.
The molecular framework of 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(pyridin-2-ylmethyl)propanamide (C21H24N4O3S) is characterized by a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
CATO manufactures 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(pyridin-2-ylmethyl)propanamide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C21H24N4O3S |
| Molecular Weight | 412.51 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 1 |
Related Dioxidothiomorpholino Standards
- (4-(1,1-Dioxidothiomorpholino)phenyl)(4-(2-fluorophenyl)piperazin-1-yl)methanone (CAS 478064-77-6)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(thiophen-2-ylmethyl)propanamide (CAS 478040-66-3)
- 2-(1,1-Dioxidothiomorpholino)-N-(furan-2-ylmethyl)-3-(1H-indol-3-yl)propanamide (CAS 478040-55-0)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-phenethylpropanamide (CAS 478040-67-4)
- 2-(1,1-Dioxidothiomorpholino)-2-phenylethyl 3,4-dichlorobenzoate (CAS 338962-92-8)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-1-morpholinopropan-1-one (CAS 478040-84-5)
- 2-(1,1-Dioxidothiomorpholino)-3-(1H-indol-3-yl)-N-(4-methoxybenzyl)propanamide (CAS 478040-65-2)
- 3-(1,1-Dioxidothiomorpholino)-3-(2-fluorophenyl)propyl furan-2-carboxylate (CAS 900015-67-0)
Recommended Standards
- 4-[(4-Methoxyphenyl)methyl]-3-[1-(3-methylthiophene-2-carbonyl)piperidin-4-yl]-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 1775544-06-3)
- 2-(1,3-Diphenyl-1H-pyrazol-4-yl)-3-(pyridin-2-ylmethyl)thiazolidin-4-one (CAS 881665-37-8)
- 1-[(3-Methoxyphenyl)methyl]-3-{1-[3-(thiophen-3-yl)-1,2,4-oxadiazol-5-yl]cyclohexyl}urea (CAS 1396680-11-7)
- 3-(Benzylthio)-4-methyl-5-(1-phenyl-5-(1H-pyrrol-1-yl)-1H-pyrazol-4-yl)-4H-1,2,4-triazole (CAS 956741-68-7)
- Tert-butyl 1-(4-amino-1,2,5-oxadiazol-3-yl)-5-methyl-1H-1,2,3-triazole-4-carboxylate (CAS 311321-42-3)
- Perfluorophenyl 1-methyl-1H-pyrazole-5-carboxylate (CAS 926921-64-4)
- 5-fluoro-4-iodo-1-(triisopropylsilyl)-1H-pyrrolo[2,3-b]pyridine (CAS 1020056-67-0)
- Methyl 4-methyloctanoate (CAS 15870-07-2)
- 1-(Pyridine-2-carbonyl)piperidine-4-carboxylic acid (CAS 67691-62-7)
- N-((1-(2-Hydroxyethyl)piperidin-4-yl)methyl)-N-isopropylacetamide (CAS 1353951-96-8)
- Methyl 5-oxo-3,5-dihydro-2H-oxazolo[2,3-b]quinazoline-8-carboxylate (CAS 1039454-98-2)
- 2H,3H,4H-chromeno[2,3-d]pyrimidine-2,4-dione (CAS 74901-20-5)
- 4-Methyl-3,3,4-trichlorobenzophenone (CAS 951891-04-6)
- Peptide Impurity 27 (CAS 1350456-68-6)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
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- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com