1-(4-Chlorophenyl)-3-(2-hydroxy-1-phenylethyl)thiourea CAS 478040-64-1
| CAS No. | 478040-64-1 |
| Molecular Formula | C15H15ClN2OS |
| Molecular Weight | 306.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The molecular framework of 1-(4-Chlorophenyl)-3-(2-hydroxy-1-phenylethyl)thiourea (C15H15ClN2OS) is characterized by a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
1-(4-Chlorophenyl)-3-(2-hydroxy-1-phenylethyl)thiourea (CAS 478040-64-1), molecular formula C15H15ClN2OS and molecular weight 306.81 g/mol, is a CATO reference standard with documented purity and traceability.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Chlorophenyl)-3-(2-hydroxy-1-phenylethyl)thiourea meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C15H15ClN2OS |
| Molecular Weight | 306.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related Chlorophenyl Standards
- (2E)-1-[2-(3-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-3-(dimethylamino)prop-2-en-1-one (CAS 1382694-68-9)
- (2E)-1-[2-(2-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-3-(dimethylamino)prop-2-en-1-one (CAS 478047-33-5)
- (2E)-1-[2-(4-Chlorophenyl)-4-methyl-1,3-thiazol-5-yl]-3-(dimethylamino)prop-2-en-1-one (CAS 308088-08-6)
- 1-(4-Chlorophenyl)-3-[(4-methoxyphenyl)sulfanyl]propan-1-one (CAS 320422-67-1)
- 2-((4-Chlorophenyl)thio)-1-(4-hydroxy-3,5-dimethylphenyl)ethan-1-one (CAS 344279-12-5)
- 2-{[(2-chlorophenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazolin-4-ol (CAS 338963-50-1)
- 2-{[(4-chlorophenyl)methyl]sulfanyl}-5,6,7,8-tetrahydroquinazolin-4-ol (CAS 338776-90-2)
- 3-((4-Chlorophenyl)thio)-1-(4-methoxyphenyl)propan-1-one (CAS 882748-88-1)
Recommended Standards
- 1-(3-Chloro-4-methoxybenzyl)-3-phenylthiourea (CAS 41966-09-0)
- 2-((2-Chloro-7-methylquinolin-3-yl)methylene)-N-ethylhydrazinecarbothioamide (CAS 477731-14-9)
- 1-Cyclopentyl-5-(propoxymethyl)-1H-pyrazole-4-sulfonyl chloride (CAS 1856019-80-1)
- 2-[(4-Aminophenyl)thio]-N-(3-chlorophenyl)-propanamide (CAS 899587-18-9)
- N-(3-chloro-4-methylphenyl)-2-(4-formyl-2-methoxyphenoxy)acetamide (CAS 579521-63-4)
- 6-Bromo-3-phenyl-[1,2,4]triazolo[4,3-a]pyridine (CAS 1260810-02-3)
- β-Carotenone (CAS 20126-74-3)
- 2-(3-Fluorobenzoyl)propanedinitrile (CAS 1463506-79-7)
- 2-[(2,4-difluorophenyl)methylamino]-2-Oxoacetic Acid (CAS 1248263-78-6)
- 925650-26-6 1-(3-Propoxyphenyl)ethan-1-amine DTXSID00586339 (CAS 925650-26-6)
- 2H-Indazol-5-amine (CAS 918903-42-1)
- 2-((Benzyloxy)carbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 1260637-46-4)
- 1-Cyclopropyl-3-(3,4,5-trifluorophenyl)propan-1-one (CAS 898778-72-8)
- Cholecystokinin, CCK Tetrapeptide (30-33) (CAS 35144-91-3)
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