2-[(4-Methylphenyl)methyl]-2H,3H,5H,6H-benzo[h]cinnolin-3-one CAS 478042-19-2
| CAS No. | 478042-19-2 |
| Molecular Formula | C20H18N2O |
| Molecular Weight | 302.37 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-[(4-Methylphenyl)methyl]-2H,3H,5H,6H-benzo[h]cinnolin-3-one (CAS 478042-19-2) is a high-purity analytical reference standard with the molecular formula C20H18N2O and a molecular weight of 302.37 g/mol.
The molecular framework of 2-[(4-Methylphenyl)methyl]-2H,3H,5H,6H-benzo[h]cinnolin-3-one (C20H18N2O) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18N2O |
| Molecular Weight | 302.37 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 2 |
Related Methylphenyl Standards
- N-(4-Methylphenyl)-5-piperidin-3-yl-1,3,4-thiadiazole-2-carboxamide (CAS 1217862-62-8)
- 2-[(4-Methylphenyl)sulfanyl]-5-nitrobenzenecarbaldehyde O-methyloxime (CAS 383147-60-2)
- 4-[(4-Methylphenyl)sulfanyl]-3-nitrobenzenecarbaldehyde O-methyloxime (CAS 477852-04-3)
- 3-(4-Methylphenyl)-2-(piperidin-1-yl)quinoline (CAS 339102-68-0)
- 4-[3-(4-Methylphenyl)-2,1-benzoxazol-5-yl]pyrimidin-2-amine (CAS 478692-83-0)
- 2-[(3-methylphenyl)amino]-4-(trifluoromethyl)-1,3-thiazole-5-carboxylic acid (CAS 886502-96-1)
- Methyl 3-[(4-methylphenyl)sulfanyl]-4-nitrobenzoate (CAS 1280787-23-6)
- 5-(4-Methylphenyl)-1H-pyrrolo[1,2-c][1,3]thiazole-6,7-dicarboxylic acid (CAS 860609-33-2)
Recommended Standards
- 2,6-Diamino-1,5-dimercaptoanthracene-9,10-dione (CAS 6409-17-2)
- 2-[[4-(4-Fluorophenyl)-4,5-dihydro-5-thioxo-1,3,4-thiadiazol-2-yl]thio]acetic acid (CAS 727704-74-7)
- 2,6-Bis(diethylamino)quinoxaline-5,8-dione (CAS 62471-82-3)
- 2-[1-(6-Methoxy-2-naphthyl)ethyl]-1H-benzimidazole (CAS 709000-02-2)
- 5-Bromo-4-(4-bromophenyl)thiazol-2-amine hydrobromide (CAS 1172108-91-6)
- N-(1-Isopentylpyrrolidin-3-yl)isoquinolin-5-amine (CAS 919120-72-2)
- 3-Chloro-N-(3-ethynylphenyl)-2,2-dimethylpropanamide (CAS 882747-28-6)
- 1H-Indole-3-carbonitrile, 4,6-dichloro-1-methyl- (CAS 2110185-90-3)
- ethyl 2,3-dihydropyrazolo[5,1-b]oxazole-6-carboxylate (CAS 623565-48-0)
- 2-(5-Methylimidazo[1,2-a]pyridin-2-yl)ethanol (CAS 943119-80-0)
- 1-Bromo-8-methylnaphthalene (CAS 33295-37-3)
- Cefixime Impurity 67 (CAS CATO-C4X-113967)
- (E)-4-(3-(4-Chlorophenyl)-3-oxoprop-1-en-1-yl)benzoic acid (CAS 525596-98-9)
- Crustacean Cardioactive Peptide (CCAP) (CAS 309247-84-5)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com