N-[6-(4-Bromophenyl)-2-oxo-2H-pyran-3-yl]benzamide CAS 478043-21-9

Purity 97%+In StockPharmaceutical Standards
CAS No.478043-21-9
Molecular FormulaC18H12BrNO3
Molecular Weight370.20 g/mol
CategoryPharmaceutical Standards / API Standards
AvailabilityIn Stock

Chemical Structure

N-[6-(4-Bromophenyl)-2-oxo-2H-pyran-3-yl]benzamide CAS 478043-21-9 chemical structure

Description

CATO supplies N-[6-(4-Bromophenyl)-2-oxo-2H-pyran-3-yl]benzamide (CAS 478043-21-9), a certified reference material (molecular formula C18H12BrNO3, MW 370.20 g/mol) for analytical method development and quality control.

Owing to a steroid core, an amide group, a hydroxyl group, an ether linkage, bromine substitution, N-[6-(4-Bromophenyl)-2-oxo-2H-pyran-3-yl]benzamide is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 370.20 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.

This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.

The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.

Physical & Chemical Properties

Molecular FormulaC18H12BrNO3
Molecular Weight370.20 g/mol
AppearancePale yellow to yellow crystalline powder. (slight halide-like odor)
Purity97%+
StorageStore at 2-8°C, protect from light, keep sealed and dry
Solubility (reference)Soluble in chloroform, dichloromethane, ethyl acetate, DMSO
StabilityMay oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions
Degree of Unsaturation (DBE)13.0
UV AbsorptionUV-absorbing
Structural FeaturesAromatic ring present
CAS Registry Year (est.)2025
Halogen ContentBr-containing
Nitrogen Atoms1

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