(3Z)-2-{[(4-fluorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole CAS 478044-90-5
| CAS No. | 478044-90-5 |
| Molecular Formula | C22H15F4N3S |
| Molecular Weight | 429.43 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
(3Z)-2-{[(4-fluorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478044-90-5) is a high-purity analytical reference standard with the molecular formula C22H15F4N3S and a molecular weight of 429.43 g/mol.
The molecular framework of (3Z)-2-{[(4-fluorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (C22H15F4N3S) is characterized by a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C22H15F4N3S |
| Molecular Weight | 429.43 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Z Standards
- (3Z)-2-{[(3-fluorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478044-92-7)
- (3R)-2-(4-Fluorophenyl)-3-[4-(phenylmethoxy)phenyl]-2-azaspiro[3.5]nonane-1,7-dione (CAS 194367-70-9)
- N-(5-(2-((4-Fluorophenyl)thio)acetyl)-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)pyrazine-2-carboxamide (CAS 1351655-23-6)
- 1-(2-Fluorophenyl)-4-(1-(3-phenoxypropyl)-1H-benzo[d]imidazol-2-yl)pyrrolidin-2-one (CAS 847396-12-7)
- N-(4-fluorophenyl)-2-(4-formyl-2-iodo-6-methoxyphenoxy)acetamide (CAS 552854-23-6)
- 1-[(1E)-{[(3-fluorophenyl)methoxy]amino}methylidene]-3-(5-iodopyridin-2-yl)thiourea (CAS 338962-73-5)
- 6-(4-((2-Fluorophenyl)sulfonyl)piperazin-1-yl)-N-(4-methylpyridin-2-yl)pyridazin-3-amine (CAS 1021114-36-2)
- 6-(4-((4-Fluorophenyl)sulfonyl)piperazin-1-yl)-N-(4-methylpyridin-2-yl)pyridazin-3-amine (CAS 1040646-39-6)
Recommended Standards
- 2-(2-Morpholinoethyl)-4-phenyl-6-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 23348-44-9)
- 2-({[4-(Benzyloxy)phenyl]methyl}({[4-(trifluoromethyl)phenyl]methyl})amino)acetic acid (CAS 1253528-19-6)
- 2-(2-Morpholinoethyl)-6-phenyl-4-(3-(trifluoromethyl)phenyl)pyridazin-3(2H)-one (CAS 23348-47-2)
- Fmoc-Arg(NO?)-OH (CAS 58111-94-7)
- 1-([1,1'-Biphenyl]-4-yl)-3-((4-bromophenyl)thio)propan-1-one (CAS 882749-10-2)
- 3-[[3,5-Bis(trifluoromethyl)phenyl]amino]-4-methoxy-3-cyclobutene-1,2-dione (CAS 1223105-85-8)
- 2-(Difluoromethyl)-5-hydroxy-4-(trifluoromethoxy)pyridine-3-carboxylic acid (CAS 1803960-52-2)
- 4-Methanesulfonyl-2-[(3-methylphenyl)formamido]butanoic acid (CAS 1025058-90-5)
- 4-Chloro-3-methyl-1-tosyl-1H-pyrrolo[2,3-b]pyridine (CAS 869335-18-2)
- Methyl 4-(2-Oxoethyl)bicyclo[2.2.1]heptane-1-carboxylate (CAS 2231673-33-7)
- 3-Bromo-2,4-dichloro-6-(trifluoromethyl)pyridine (CAS 1214330-62-7)
- 4-Chloro-N-[(Z)-2-[4-(4-methoxyphenyl)-5-(trifluoromethyl)-4H-1,2,4-triazol-3-yl]-2-nitroethenyl]aniline (CAS 400079-84-7)
- 4-Methyl-N-(2-methylpentan-3-yl)pyridin-3-amine (CAS 1339849-06-7)
- D-Ser39-Tirzepatide (CAS CATO-CPTD788694)
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