(3Z)-2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole CAS 478045-15-7
| CAS No. | 478045-15-7 |
| Molecular Formula | C22H14Cl2F3N3S |
| Molecular Weight | 480.33 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
(3Z)-2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478045-15-7) is a high-purity analytical reference standard with the molecular formula C22H14Cl2F3N3S and a molecular weight of 480.33 g/mol.
Structurally, (3Z)-2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (C22H14Cl2F3N3S) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality, fluorine/chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 15.0, corresponding to approximately 15 ring(s) or double-bond equivalent(s). With a molecular weight of 480.33 g/mol, it falls into the moderately-high-molecular-weight range. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), (3Z)-2-{[(2,4-dichlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C22H14Cl2F3N3S |
| Molecular Weight | 480.33 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
Related Z Standards
- (3Z)-2-{[(2,6-dichlorophenyl)methyl]sulfanyl}-3-{2-[3-(trifluoromethyl)phenyl]hydrazin-1-ylidene}-3H-indole (CAS 478045-13-5)
- (3Z)-3-{[(2,4-dichlorophenyl)methoxy]imino}-1-[(2,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indol-2-one (CAS 303996-94-3)
- (3Z)-3-{[(2,4-dichlorophenyl)methoxy]imino}-1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indol-2-one (CAS 477853-29-5)
- (3Z)-3-{[(2,6-dichlorophenyl)methoxy]imino}-1-[(3,4-dichlorophenyl)methyl]-2,3-dihydro-1H-indol-2-one (CAS 303996-89-6)
- (5-((3,5-Dichlorophenyl)thio)-4-isopropyl-1-(3-(pyridin-2-yl)propyl)-1H-imidazol-2-yl)methyl carbamate (CAS 178980-23-9)
- 3-(5-((3,5-Dichlorophenyl)thio)-4-isopropyl-1-(pyridin-4-ylmethyl)-1H-imidazol-2-yl)propyl carbamate (CAS 178980-45-5)
- 4'-(2,4-Dichlorophenyl)-1'-methyldispiro[chromane-3,3'-pyrrolidine-2',3''-indoline]-2'',4-dione (CAS 1212332-83-6)
- 4'-(3,4-Dichlorophenyl)-1'-methyl-1'',2,2'',4-tetrahydrodispiro[1-benzopyran-3,3'-pyrrolidine-2',3''-indole]-2'',4-dione (CAS 1797910-69-0)
Recommended Standards
- 2-((5-(((4-Iodophenyl)amino)methyl)-4-phenyl-4H-1,2,4-triazol-3-yl)thio)acetohydrazide (CAS 1071351-15-9)
- Clindamycin Impurity 83 (CAS CATO-C4X-134183)
- Fmoc-3-bromo-L-homophenylalanine (CAS 1260590-73-5)
- Crizotinib Impurity 43 (CAS CATO-C4X-102543)
- rel-(2R,3R)-tert-Butyl 2-(hydroxymethyl)-3-methylpyrrolidine-1-carboxylate (CAS 2088521-68-8)
- 7H-pyrazolo[4,3-d]pyrimidin-7-one, 1,4,5,6-tetrahydro-3-(1-methylethyl)-5-thioxo- (CAS 1289139-26-9)
- 2-Ethyl-4-fluoro-1-nitrobenzene (CAS 1089279-29-7)
- Methyl (2,2,2-Trifluoroethyl) Carbonate (CAS 156783-95-8)
- (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilanyloxy)methyl]pyrrolidine (S)-2-[(Bis(3,5-bis(trifluoromethyl)phenyl)trimethylsilyloxy)methyl]pyrrolidine (S)-|A,|A-Bis[3,5-bis(trifluoromethyl)phenyl]-2-pyrrolidinemethanol trimethylsilyl ether (S)-|A,|A-[3,5-Bis(trifluoromethyl)phenyl]prolinol trimethylsilyl ether 848821-61-4 (CAS 848821-61-4)
- (R)-1-(3,5-bis(trifluoromethyl)phenyl)but-3-en-1-amine (CAS 1270190-15-2)
- 3-Cyclopropylimidazo[1,5-a]pyridin-1-amine (CAS 1558193-56-8)
- 6-Bromo-2-(p-tolyl)imidazo[1,2-a]pyridine-3-carbaldehyde (CAS 820245-77-0)
- 7-Fluoro-4-hydroxyindolin-2-one (CAS 1033810-96-6)
- Semaglutide impurity 85 (CAS CATO-C4X-222685)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com