2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide CAS 478045-36-2
| CAS No. | 478045-36-2 |
| Molecular Formula | C17H12F4N4O3S3 |
| Molecular Weight | 492.49 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 492.49 g/mol gives 2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide (CAS 478045-36-2), molecular formula C17H12F4N4O3S3 and molecular weight 492.49 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide (C17H12F4N4O3S3) contains a steroid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, fluorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 12.0, corresponding to approximately 12 ring(s) or double-bond equivalent(s). With a molecular weight of 492.49 g/mol, it falls into the moderately-high-molecular-weight range. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}-N-[5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl]acetamide meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C17H12F4N4O3S3 |
| Molecular Weight | 492.49 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 3 |
Related fluorobenzenesulfonamido Standards
- Methyl 3-(2-{[2-(4-fluorobenzenesulfonamido)phenyl]sulfanyl}acetamido)thiophene-2-carboxylate (CAS 477869-08-2)
- 3,5-Bis(4-fluorobenzenesulfonamido)benzoic acid (CAS 329908-32-9)
- Ethyl 4-[3-(4-fluorobenzenesulfonamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-33-7)
- Methyl 2-[2-(4-fluorobenzenesulfonamido)acetamido]-4-(methylsulfanyl)butanoate (CAS 1397007-12-3)
- 2-(4-Fluorobenzenesulfonamido)-1,3-benzothiazole-6-carboxylic acid (CAS 929854-37-5)
- 3-(4-Fluorobenzenesulfonamido)naphthalene-2-carboxylic acid (CAS 926200-59-1)
- 2-(2-Fluorobenzenesulfonamido)-3-phenylpropanoic acid (CAS 1009227-82-0)
- (2s)-2-(2-Fluorobenzenesulfonamido)-3-phenylpropanoic acid (CAS 1212370-86-9)
Recommended Standards
- 2-((2-((2-Fluorophenyl)sulfonamido)phenyl)thio)-N-(5-(trifluoromethyl)-1,3,4-thiadiazol-2-yl)acetamide (CAS 478045-38-4)
- S-(2-(N-((4-Amino-2-methylpyrimidin-5-yl)methyl)formamido)-5-(phosphonooxy)pent-2-en-3-yl) 3-phenylprop-2-enethioate (CAS 751-21-3)
- Ac-muramyl-D-Ala-D-Glu-NH? (CAS 56816-18-3)
- Tucatinib Impurity 39 (CAS CATO-C4X-260539)
- (4-Chlorophenyl)(3-(pyrrolidin-1-yl)-5-(trifluoromethyl)pyridin-2-yl)methanone (CAS 338959-79-8)
- 7-Chloro-3-(cyclopropylmethyl)-8-(trifluoromethyl)-[1,2,4]triazolo[4,3-a]pyridine, 97% (CAS 1254981-30-0)
- 1-(4-Methoxy-2,3-dimethylphenyl)ethanone (CAS 41068-27-3)
- Raltegravir EP Impurity C (CAS 1391918-17-4)
- Boc-d-thyroxine (CAS 89624-64-6)
- 4-(Aminomethyl)thian-4-ol (CAS 879514-92-8)
- 5-((1,3-Diphenyl-1H-pyrazol-4-yl)methylene)-3-((tetrahydrofuran-2-yl)methyl)-2-thioxothiazolidin-4-one (CAS 623940-40-9)
- 2-(5-((Ethoxycarbonyl)carbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)ethyl 3-chlorobenzoate (CAS 303997-30-0)
- Sivelestat sodium impurity 45 (CAS CATO-C4X-212345)
- Tau Peptide (268-282) trifluoroacetate salt (CAS 330456-37-6)
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