1-(Cyclopropylmethyl)-3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one CAS 478045-86-2
| CAS No. | 478045-86-2 |
| Molecular Formula | C16H15Cl2NO2 |
| Molecular Weight | 324.20 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 324.20 g/mol gives 1-(Cyclopropylmethyl)-3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
1-(Cyclopropylmethyl)-3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (CAS 478045-86-2), molecular formula C16H15Cl2NO2 and molecular weight 324.20 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 1-(Cyclopropylmethyl)-3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one (C16H15Cl2NO2) contains a nitrogen-containing heterocyclic scaffold, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 324.20 g/mol, it falls into the moderately-high-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
As a certified reference material (CRM), 1-(Cyclopropylmethyl)-3-[(2,4-dichlorophenyl)methyl]-4-hydroxy-1,2-dihydropyridin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C16H15Cl2NO2 |
| Molecular Weight | 324.20 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Cyclopropylmethyl Standards
- 1-(Cyclopropylmethyl)-4-(2-(1-methyl-1H-pyrazol-5-yl)pyrimidin-5-yl)-1H-pyrrole-2-carboxylic acid (CAS 1422063-24-8)
- n-(Cyclopropylmethyl)-4-[(cyclopropylmethyl)amino]-2-nitrobenzene-1-sulfonamide (CAS 1221726-11-9)
- 1-(Cyclopropylmethyl)-3-methyl-4-(4-phenoxyphenyl)-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860789-20-4)
- 1-(Cyclopropylmethyl)-4-(2-(pyridin-3-yl)pyrimidin-5-yl)-1H-pyrrole-2-carboxylic acid (CAS 1422138-22-4)
- 1-(Cyclopropylmethyl)-4-(2-morpholinopyrimidin-5-yl)-1H-pyrrole-2-carboxylic acid (CAS 1422060-59-0)
- 1-(Cyclopropylmethyl)-4-(2-phenylpyrimidin-5-yl)-1H-pyrrole-2-carboxylic acid (CAS 1422060-99-8)
- n-(Cyclopropylmethyl)-4-fluoro-2-iodobenzamide (CAS 1147669-43-9)
- N-(cyclopropylmethyl)-1-(2-hydroxy-2-(2-methoxyphenyl)ethyl)-1H-1,2,3-triazole-4-carboxamide (CAS 1396680-43-5)
Recommended Standards
- 6-Chloro-3-(3-chloro-4-ethoxyphenyl)-3,4-dihydro-2H-benzo[b][1,4]oxazine (CAS 1710472-06-2)
- 1-(Dichloromethyl)-N-(furan-2-ylmethyl)-2,3-dihydro-1H-indene-2-carboxamide (CAS 263256-07-1)
- N-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyridine-3-sulfonamide (CAS 1416337-90-0)
- 10-(3,4-Dichlorophenyl)benzo[h]quinoline (CAS 952606-24-5)
- Tetrabutylammonium (triiodide) (CAS 13311-45-0)
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- 2-(2-Oxo-2-(pyridin-3-yl)ethyl)malononitrile (CAS 857663-88-8)
- Methyl 5-ethoxy-2-vinylbenzoate (CAS 223750-55-8)
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