1-(4-Chlorobenzyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one CAS 478045-92-0
| CAS No. | 478045-92-0 |
| Molecular Formula | C19H14Cl3NO2 |
| Molecular Weight | 394.68 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 1-(4-Chlorobenzyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one.
CATO supplies 1-(4-Chlorobenzyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one (CAS 478045-92-0), a certified reference material (molecular formula C19H14Cl3NO2, MW 394.68 g/mol) for analytical method development and quality control.
The molecular framework of 1-(4-Chlorobenzyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one (C19H14Cl3NO2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 1-(4-Chlorobenzyl)-3-(2,4-dichlorobenzyl)-4-hydroxypyridin-2(1H)-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C19H14Cl3NO2 |
| Molecular Weight | 394.68 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 1 |
Related Chlorobenzyl Standards
- 1-(3-Chlorobenzyl)-3-(4-phenyl-5-thioxo-4,5-dihydro-1H-1,2,4-triazol-3-yl)pyridin-2(1H)-one (CAS 677749-35-8)
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Recommended Standards
- (E)-[(5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methylidene][(2,4-dichlorophenyl)methoxy]amine (CAS 321538-43-6)
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- 3-Chloro-2-(5-(methylsulfonyl)-3-(trifluoromethyl)-1H-1,2,4-triazol-1-yl)-5-(trifluoromethyl)pyridine (CAS 1823183-57-8)
- 2,3,5,6-Tetrabromopyridine (CAS 2766-64-5)
- N-benzyl-2-((2,3-dichlorophenyl)thio)-N-(4-methoxyphenyl)acetamide (CAS 860788-20-1)
- 2-(3,4-Dihydroquinolin-1(2H)-yl)-N-(4-methoxyphenyl)acetamide (CAS 882749-32-8)
- Ethyl 4,5,6,7-Tetrahydrothiazolo[5,4-c]pyridine-2-carboxylate Hydrochloride (CAS 1186663-33-1)
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- 3-(tert-Butyl)-6-isopropylcyclohexa-3,5-diene-1,2-dione (CAS 168331-80-4)
- 4-Chloro-5-iodo-2-methoxyaniline (CAS 1508278-49-6)
- 5-Bromo-2-methyl-3-nitrobenzoic Acid (CAS 107650-20-4)
- 2-(Thiophen-3-yl)acetamide (CAS 13781-66-3)
- tert-Butyl ((4-methyl-1H-imidazol-2-yl)methyl)carbamate (CAS 1595757-86-0)
- Semaglutide impurity 108 (CAS CATO-C4X-2226108)
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