2-((4-Fluorophenyl)thio)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one CAS 478047-47-1
| CAS No. | 478047-47-1 |
| Molecular Formula | C18H14FNOS2 |
| Molecular Weight | 343.44 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
2-((4-Fluorophenyl)thio)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one (CAS 478047-47-1) is a high-purity analytical reference standard with the molecular formula C18H14FNOS2 and a molecular weight of 343.44 g/mol.
The molecular framework of 2-((4-Fluorophenyl)thio)-1-(4-methyl-2-phenylthiazol-5-yl)ethan-1-one (C18H14FNOS2) is characterized by a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine substitution. In reversed-phase chromatography, its retention is governed primarily by its high hydrophobicity (logP), which provides a practical basis for HPLC-UV/DAD or LC-MS method development. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C18H14FNOS2 |
| Molecular Weight | 343.44 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in chloroform, dichloromethane, ethyl acetate, DMSO |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 1 |
| Sulfur Atoms | 2 |
Related Fluorophenyl Standards
- 2-(4-Fluorophenyl)-N-(2-(1-methyl-4-(thiophen-2-yl)-1H-imidazol-2-yl)ethyl)acetamide (CAS 1396764-96-7)
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- 3-(2-Fluorophenyl)-N-(furan-3-ylmethyl)-N-(thiophen-2-ylmethyl)propanamide (CAS 1797214-33-5)
- (3-(4-Fluorophenyl)azepan-1-yl)(2-(methylthio)phenyl)methanone (CAS 1797545-94-8)
- (2Z)-2-[(2-Fluorophenyl)methylidene]-1-azabicyclo[2.2.2]octan-3-yl thiophene-2-carboxylate (CAS 477871-49-1)
- N-(2-((4-(4-Fluorophenyl)piperazin-1-yl)sulfonyl)ethyl)propionamide (CAS 897618-38-1)
- N-{[4-(2-Fluorophenyl)piperazino]carbothioyl}benzenecarboxamide (CAS 881814-87-5)
- (5-(4-Fluorophenyl)-3-(prop-2-yn-1-ylthio)-1H-1,2,4-triazol-1-yl)(thiophen-2-yl)methanone (CAS 1024198-99-9)
Recommended Standards
- 1-Benzyl-N'-(thiophene-2-carbonyl)piperidine-4-carbohydrazide (CAS 478064-42-5)
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- 1-Benzyl-3,4-diphenyl-1H-1,2,4-triazole-5(4H)-thione (CAS 62353-91-7)
- 2-(5-Methoxy-2-(p-tolylsulfinyl)phenyl)-4,4-dimethyl-4,5-dihydrooxazole (CAS 2185788-98-9)
- Acemetacin Impurity 1 (CAS 77914-62-6)
- O-(4-isopropylbenzyl)hydroxylamine (CAS 706751-57-7)
- 2-PYRIDIN-3-YL PIPERAZINE 3HCL (CAS 1171887-03-8)
- 1-(Chloromethoxy)-2-methylpropane (CAS 34180-11-5)
- 2-(2-Bromophenoxy)-4-methyl-1-nitrobenzene (CAS 1516187-55-5)
- 1-(2-Ethoxy-3-methylphenyl)-N-methylmethanamine (CAS 709649-55-8)
- 3-Ethoxyazetidine (CAS 88536-21-4)
- 2-(2,4-Dimethoxyphenyl)-5-isopentyl-4,6-dimethoxybenzofuran (CAS 66056-44-8)
- 3-Chloro-4-(difluoromethoxy)benzimidamide (CAS 1250558-67-8)
- D-[Ser]8-Semaglutide (CAS CATO-CPTD788632)
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