(E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-chlorobenzoate CAS 478047-82-4
| CAS No. | 478047-82-4 |
| Molecular Formula | C18H16ClN3O2 |
| Molecular Weight | 341.79 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-chlorobenzoate.
(E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-chlorobenzoate (CAS 478047-82-4) is a high-purity analytical reference standard with the molecular formula C18H16ClN3O2 and a molecular weight of 341.79 g/mol.
The molecular framework of (E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-chlorobenzoate (C18H16ClN3O2) is characterized by a steroid core, an amide group, a hydroxyl group, an ether linkage, chlorine substitution. In reversed-phase chromatography, its retention is governed primarily by the protonation state of its nitrogen-containing groups, which provides a practical basis for HPLC-UV/DAD or LC-MS method development. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), (E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-chlorobenzoate meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C18H16ClN3O2 |
| Molecular Weight | 341.79 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 12.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
Related E Standards
- 4-((2,7-Dimethylimidazo[1,2-a]pyridine-3-carboxamido)methyl)benzoic acid (CAS 1181266-00-1)
- (E)-(1-{2,7-dimethylimidazo[1,2-a]pyridin-3-yl}ethylidene)amino 4-methylbenzoate (CAS 478047-81-3)
- 2-(2-(2,3-Dimethylimidazo[1,2-b][1,2,4]triazin-7-yl)ethyl)isoindoline-1,3-dione (CAS 1170459-36-5)
- 3-(4-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)thiazol-2-yl)aniline (CAS 1416338-86-7)
- 1-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-2-((3-(trifluoromethyl)phenyl)thio)ethan-1-one (CAS 478042-08-9)
- 4-[[4-(2,7-Dimethylimidazo[1,2-α]pyridin-3-yl)-2-thiazolyl]amino]benzoic Acid (CAS 315704-15-5)
- 3-(2,6-Dimethylimidazo[2,1-b]thiazol-5-yl)-N-(4-methylthiazol-2-yl)acrylamide (CAS 924863-16-1)
- 1-(2,7-Dimethylimidazo[1,2-a]pyridin-3-yl)-2-[(4-fluorophenyl)sulfanyl]-1-ethanone (CAS 478042-05-6)
Recommended Standards
- (5-Chloro-1-methyl-3-phenyl-1H-pyrazol-4-yl)methyl phenylcarbamate (CAS 318248-39-4)
- (E)-4-(((4-chloro-6-methylpyrimidin-2-yl)imino)methyl)-5-hydroxy-1,6-dihydro-[1,1'-biphenyl]-3(2H)-one (CAS 946387-26-4)
- (4Z)-4-{[(4-chlorophenyl)amino]methylidene}-3-ethoxy-1-phenyl-4,5-dihydro-1H-pyrazol-5-one (CAS 338750-93-9)
- 1-(2-chlorobenzyl)-6-cyclopropyl-3-methyl-1H-pyrazolo[3,4-b]pyridine-4-carboxylic acid (CAS 937598-76-0)
- Trimethylsilyl pentafluoropropionate (CAS 24930-02-7)
- 2-[(2R)-Pyrrolidin-2-yl]ethan-1-amine (CAS 1053182-84-5)
- 4-(2-Aminoethyl)-5-methylisoxazol-3(2H)-one (CAS 58728-68-0)
- Ethyl 5-(4-chlorophenyl)-5-oxopentanoate (CAS 54029-03-7)
- 4-Bromobenzonitrile (CAS 623-00-7)
- 2-Chloroethyl (5-bromothiazol-2-yl)carbamate (CAS 353265-54-0)
- Testosterone Impurity 38 (CAS CATO-C4X-243238)
- 3-(2-Bromobenzyl)oxetane (CAS 1823939-89-4)
- n1,n2-Dimethyl-n1-(oxetan-3-yl)ethane-1,2-diamine (CAS 2152143-31-0)
- Semaglutide Impurity 125 xTFA Salt (CAS CATO-C4X-2226125)
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