1-[(6-Chloropyridin-3-yl)methyl]-4-(4-fluorophenyl)piperazine CAS 478048-50-9
| CAS No. | 478048-50-9 |
| Molecular Formula | C16H17ClFN3 |
| Molecular Weight | 305.78 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
1-[(6-Chloropyridin-3-yl)methyl]-4-(4-fluorophenyl)piperazine (C16H17ClFN3) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
1-[(6-Chloropyridin-3-yl)methyl]-4-(4-fluorophenyl)piperazine (CAS 478048-50-9) is a high-purity analytical reference standard with the molecular formula C16H17ClFN3 and a molecular weight of 305.78 g/mol.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures 1-[(6-Chloropyridin-3-yl)methyl]-4-(4-fluorophenyl)piperazine under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C16H17ClFN3 |
| Molecular Weight | 305.78 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor, low volatility) |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
Related Chloropyridin Standards
- Methyl 1-(3-chloropyridin-2-yl)-3-(trifluoromethyl)-1H-pyrazole-5-carboxylate (CAS 1055071-09-4)
- 5-(3-Chloropyridin-2-yl)-1-(2,2,2-trifluoroethyl)-1H-pyrazole-4-carboxylic acid (CAS 1423030-58-3)
- 1-[(2-chloropyridin-3-yl)sulfonyl]piperidine-4-carboxylic acid (CAS 929975-76-8)
- N-(5-chloropyridin-2-yl)-5-methoxy-2-nitrobenzamide (CAS 280773-16-2)
- N1-(5-Chloropyridin-2-yl)-N2-(2-(2-methyl-1H-imidazol-1-yl)ethyl)oxalamide (CAS 1208546-56-8)
- 1-[(2-Chloropyridin-3-yl)sulfonyl]piperidine-4-carboxamide (CAS 1156723-20-4)
- 2-(2-Chloropyridin-4-yl)-4-(2,6-difluorophenyl)thiazole (CAS 1431728-71-0)
- 4-((2-Chloropyridin-4-yl)methyl)-1-(methylsulfonyl)azepane (CAS 1316218-00-4)
Recommended Standards
- 1-(2-chlorobenzoyl)-4-phenyl-3-thiosemicarbazide (CAS 26036-04-4)
- 1-Chloro-3-(isocyano(tosyl)methyl)benzene (CAS 321345-35-1)
- {[(2E)-2-(4-chlorophenyl)-2-(methoxyimino)ethyl]sulfamoyl}dimethylamine (CAS 672951-79-0)
- 2-(3-(4-Chlorophenyl)-6-methylpyrazin-2-yl)thiazolidin-4-one (CAS 89467-17-4)
- tert-Butyl 2-isopropylpiperazine-1-carboxylate hydrochloride (CAS 1203011-26-0)
- 1-Bromo-4-(bromomethyl)-5-fluoro-2-methylbenzene (CAS 2090512-31-3)
- 2,3-Dihydro-benzo[1,4]oxazine-2,4-dicarboxylic acid 4-tert-butyl ester (CAS 939525-77-6)
- 5-Bromo-4-cyclopropyl-6-methoxypyrimidine (CAS 1649454-57-8)
- 5-Ethynyl-3-methoxythiophene-2-carbaldehyde (CAS 2314461-42-0)
- 2-(2-((4-Methoxyphenyl)thio)ethyl)piperidine (CAS 1284431-74-8)
- 3-(Benzylamino)tetrahydrothiophene 1,1-dioxide (CAS 321580-44-3)
- 4-[(2,4-Dichlorophenyl)sulfanyl]-6-(4-methylphenyl)-2-(methylsulfanyl)pyrimidine-5-carbonitrile (CAS 303984-99-8)
- 5,5-Difluoro-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidine hydrochloride (CAS 2306261-61-8)
- Liraglutide Impurity 26 (CAS CATO-C4X-199226)
Why CATO?
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- 130,000+ catalog items in stock, COA supplied with every batch
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