3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-(4-methoxyphenyl)-1-phenylazetidin-2-one CAS 478049-87-5
| CAS No. | 478049-87-5 |
| Molecular Formula | C27H28FN3O2 |
| Molecular Weight | 445.53 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Compared with other compounds in its class, the molecular weight of 445.53 g/mol gives 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-(4-methoxyphenyl)-1-phenylazetidin-2-one distinctive chromatographic separation conditions and mass-spectrometry parameter settings.
3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-(4-methoxyphenyl)-1-phenylazetidin-2-one (CAS 478049-87-5) is a high-purity analytical reference standard with the molecular formula C27H28FN3O2 and a molecular weight of 445.53 g/mol.
Based on its molecular formula C27H28FN3O2, 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-(4-methoxyphenyl)-1-phenylazetidin-2-one contains a steroid core, an amide group, a hydroxyl group, an ether linkage, fluorine substitution; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 445.53 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
As a certified reference material (CRM), 3-{[4-(2-fluorophenyl)piperazin-1-yl]methyl}-4-(4-methoxyphenyl)-1-phenylazetidin-2-one meets the metrological traceability requirements of ISO/IEC 17025 laboratories. Batch-to-batch consistency is monitored via control charts to guarantee comparable assigned values across lots.
Physical & Chemical Properties
| Molecular Formula | C27H28FN3O2 |
| Molecular Weight | 445.53 g/mol |
| Appearance | Pale yellow to yellow crystalline powder. (slight halide-like odor) |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F-containing |
| Nitrogen Atoms | 3 |
Related fluorophenyl Standards
- 4-((4-Fluorophenyl)sulfonyl)-5-((1-phenylethyl)thio)-2-(thiophen-2-yl)oxazole (CAS 850927-93-4)
- 8-((4-Fluorophenyl)sulfonyl)-2-phenyl-3-(propylthio)-1,4,8-triazaspiro[4.5]deca-1,3-diene (CAS 932496-97-4)
- 2-(4-((4-(2-Fluorophenyl)piperazin-1-yl)sulfonyl)-1-oxoisoquinolin-2(1H)-yl)acetic acid (CAS 685523-89-1)
- 1-(1-((4-Fluorophenyl)sulfonyl)piperidin-4-yl)-3-(3-(trifluoromethyl)phenyl)urea (CAS 672950-45-7)
- Ethyl 5-(2-{[(4-fluorophenyl)carbamoyl]carbonyl}-1H-pyrrol-1-yl)-1-phenyl-1H-pyrazole-4-carboxylate (CAS 477709-27-6)
- 2-(4-Fluorophenyl)-4-(3-hydroxy-3-methylbutoxy)-5-(4-(methylsulfonyl)phenyl)pyridazin-3(2H)-one (CAS 221030-56-4)
- 2-((5-Benzyl-4-(4-fluorophenyl)-4H-1,2,4-triazol-3-yl)thio)-N-(4-ethylphenyl)acetamide (CAS 763139-01-1)
- Ethyl 2-(2-{[(3-fluorophenyl)methyl]sulfanyl}-4,5-diphenyl-1H-imidazol-1-yl)acetate (CAS 339277-97-3)
Recommended Standards
- 2-((6-(1,1-Dicyanoprop-1-en-2-yl)naphthalen-2-yl)(methyl)amino)ethyl 4-methylbenzenesulfonate (CAS 259739-02-1)
- 5-(1-Hydroxyethyl)-N,N-bis(4-methoxybenzyl)-1-methyl-1H-pyrazole-3-sulfonamide (CAS 2281769-17-1)
- (S)-N-(1-Phenylpropyl)-2-(quinoline-8-sulfonamido)benzamide (CAS 478262-95-2)
- Cyclopentyl 4-(4-fluorophenyl)-2-methyl-5-oxo-7-phenyl-1,4,5,6,7,8-hexahydroquinoline-3-carboxylate (CAS 5803-68-9)
- 2-(tert-butoxycarbonyl)-6-methoxy-1,2,3,4-tetrahydroisoquinoline-1-carboxylic acid (CAS 499139-27-4)
- 3-Amino-8-methoxyquinoline-6-carboxylic acid (CAS 2721373-57-3)
- 9-Ethyl-N,N-dimethyl-9H-purin-6-amine (CAS 5427-22-5)
- 2-(2-(Trifluoromethyl)benzoyl)phenyl acetate (CAS 890098-93-8)
- Protosappanin B (CAS 102036-29-3)
- n-(Thiazol-5-ylmethyl)pentan-1-amine (CAS 1340035-00-8)
- Relugolix Impurity 104 (CAS CATO-C4X-2429104)
- (3R,5R)-5-methylpyrrolidin-3-amine dihydrobromide (CAS 144043-32-3)
- N-(4-(Acridin-9-ylamino)butyl)-4-(bis(2-chloroethyl)amino)benzamide (CAS 125173-78-6)
- Semaglutide impurity 93 (CAS CATO-C4X-222693)
Why CATO?
- ISO 17034 accredited reference material producer (CNAS + ANAB dual accreditation)
- 130,000+ catalog items in stock, COA supplied with every batch
- Worldwide shipping with full export documentation (HS code guidance available)
- Technical support: +86 18665070610 / Nicole.chen@cato-chem.com