2-({2-[(2-chloro-1,3-thiazol-5-yl)methoxy]-1-naphthyl}methylene)malononitrile CAS 478064-73-2
| CAS No. | 478064-73-2 |
| Molecular Formula | C18H10ClN3OS |
| Molecular Weight | 351.81 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
2-({2-[(2-chloro-1,3-thiazol-5-yl)methoxy]-1-naphthyl}methylene)malononitrile (CAS 478064-73-2) is a high-purity analytical reference standard with the molecular formula C18H10ClN3OS and a molecular weight of 351.81 g/mol.
2-({2-[(2-chloro-1,3-thiazol-5-yl)methoxy]-1-naphthyl}methylene)malononitrile (C18H10ClN3OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C18H10ClN3OS |
| Molecular Weight | 351.81 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 15.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |
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Recommended Standards
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- tert-Butyl 2-propylpiperazine-1-carboxylate (CAS 1027511-67-6)
- 2-(Bromomethyl)-3,3-dimethylbut-1-ene (CAS 3854-52-2)
- 4,4’-[(1-Phenylpyrazole-3,5-diyl)bis(ethene-2,1-diyl)]diphenol (CAS 828911-79-1)
- Kaolinite (CAS 1318-74-7)
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- 103244-41-3 Insulin-like Growth Factor-II fragment 33-40 Ser-Arg-Val-Ser-Arg-Arg-Ser-Arg (CAS 103244-41-3)
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