(2E)-3-[(4-Bromophenyl)amino]-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one CAS 478064-92-5
| CAS No. | 478064-92-5 |
| Molecular Formula | C19H14BrClN2OS |
| Molecular Weight | 433.75 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including (2E)-3-[(4-Bromophenyl)amino]-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one.
CATO supplies (2E)-3-[(4-Bromophenyl)amino]-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one (CAS 478064-92-5), a certified reference material (molecular formula C19H14BrClN2OS, MW 433.75 g/mol) for analytical method development and quality control.
(2E)-3-[(4-Bromophenyl)amino]-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one (C19H14BrClN2OS) contains a steroid core, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, chlorine/bromine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. The high carbon-to-hydrogen ratio imparts good lipophilicity, allowing liquid-liquid extraction with non-polar solvents such as n-hexane or ethyl acetate.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures (2E)-3-[(4-Bromophenyl)amino]-1-[2-(4-chlorophenyl)-4-methyl-1,3-thiazol-5-yl]prop-2-en-1-one under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
Physical & Chemical Properties
| Molecular Formula | C19H14BrClN2OS |
| Molecular Weight | 433.75 g/mol |
| Purity | 97%+ |
| Storage | Store at room temperature, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl/Br-containing |
| Nitrogen Atoms | 2 |
| Sulfur Atoms | 1 |
Related E Standards
- 5-Acetyl-3-[(4-bromophenyl)methyl]-1-(4-chlorophenyl)-1,2,3,4-tetrahydropyrimidine-2,4-dione (CAS 321432-29-5)
- 4-(4-Bromophenyl)-1-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]-3-methyl-4,5-dihydro-1H-1,2,4-triazol-5-one (CAS 860644-56-0)
- 5-((4-Bromophenyl)thio)-1-methyl-3-((p-tolylthio)methyl)-1H-pyrazole-4-carbaldehyde (CAS 400823-20-3)
- (4-(4-Bromophenyl)-1,1-dioxido-4H-benzo[b][1,4]thiazin-2-yl)(pyrrolidin-1-yl)methanone (CAS 1251624-24-4)
- N-(4-bromophenyl)-2-(4-methoxyphenyl)quinoline-4-carboxamide (CAS 312321-04-3)
- 1,3-Bis[(4-bromophenyl)sulfanyl]propan-2-ol (CAS 400081-04-1)
- 5-((6-(4-Bromophenyl)imidazo[2,1-b]thiazol-5-yl)methylene)-2,2-dimethyl-1,3-dioxane-4,6-dione (CAS 439107-47-8)
- Methyl 3-(2-{[(4-bromophenyl)carbamoyl]carbonyl}-1H-pyrrol-1-yl)thiophene-2-carboxylate (CAS 477857-81-1)
Recommended Standards
- Ferroquine (CAS 185055-67-8)
- (3RS)-3-(2-Benzyloxy-5-methylphenyl)-N,N-bis(1-methylethyl)-3-phenylpropan-1-amine (CAS 389068-22-8)
- 7-(benzenesulfonyl)-4-chloro-6-iodo-7H-pyrrolo[2,3-d]pyrimidine (CAS 876343-09-8)
- 5-Chloro-3-iodo-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazole-6-carbonitrile (CAS 2876897-96-8)
- N-(m-tolyl)morpholine-3-carboxamide (CAS 1493618-07-7)
- methyl 2-chloropyrimidine-5-carboxylate (CAS 287714-35-6)
- 3-Morpholino-1-phenyl-5,6-dihydropyridin-2(1H)-one (CAS 1197377-73-3)
- 4-(Cyclohexyloxy)benzenesulfonamide (CAS 100370-86-3)
- (2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)diphenylphosphine oxide (CAS 445380-60-9)
- 2-Amino-6-chloro-1,3-benzoxazole-5-carboxylic acid (CAS 1820684-94-3)
- 6-(Aminomethyl)-3-(difluoromethyl)-5-fluoropyridin-2-amine (CAS 1806814-71-0)
- 1-methyl-2,3-dihydro-1H-indole-3-carbaldehyde (CAS 933705-26-1)
- 4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)benzenesulfonyl fluoride (CAS 1337505-77-7)
- Semaglutide impurity 70 (CAS CATO-C4X-222670)
Why CATO?
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