Ethyl 4-[3-(4-chlorobenzenesulfonamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate CAS 478065-14-4
| CAS No. | 478065-14-4 |
| Molecular Formula | C20H18ClN3O5S2 |
| Molecular Weight | 479.96 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including Ethyl 4-[3-(4-chlorobenzenesulfonamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate.
Ethyl 4-[3-(4-chlorobenzenesulfonamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate (CAS 478065-14-4), molecular formula C20H18ClN3O5S2 and molecular weight 479.96 g/mol, is a CATO reference standard with documented purity and traceability.
Owing to a flavonoid core, an amide group, a sulfone group, a hydroxyl group, an ether linkage, chlorine substitution, Ethyl 4-[3-(4-chlorobenzenesulfonamido)phenoxy]-2-(methylsulfanyl)pyrimidine-5-carboxylate is typically pale yellow to yellow crystalline powder. Its solid-state physicochemical attributes — including a molecular weight of 479.96 g/mol — guide the selection of appropriate sample preparation and analytical techniques. The aromatic system may exhibit native fluorescence, enabling detection with a fluorescence detector (FLD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C20H18ClN3O5S2 |
| Molecular Weight | 479.96 g/mol |
| Purity | 97%+ |
| Storage | Store in a cool place (≤25°C), protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening; Contains ester bond; hydrolyzes under strong alkaline conditions |
| Degree of Unsaturation (DBE) | 13.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 2 |
Related Ethyl Standards
- Methyl 2-({5-[1-(4-chlorobenzenesulfonamido)-2-phenylethyl]-4-methyl-4H-1,2,4-triazol-3-yl}sulfanyl)acetate (CAS 338794-32-4)
- Methyl 3-(2-{[2-(2-chlorobenzenesulfonamido)phenyl]sulfanyl}acetamido)thiophene-2-carboxylate (CAS 477887-57-3)
- Methyl 3-(2-{[2-(4-chlorobenzenesulfonamido)phenyl]sulfanyl}acetamido)thiophene-2-carboxylate (CAS 477869-11-7)
- N-[2-(2-Chlorobenzenesulfonamido)ethyl]-2,5-bis(2,2,2-trifluoroethoxy)benzamide (CAS 338404-60-7)
- 2-(4-Chlorobenzenesulfonamido)ethyl N-(3,4-dichlorophenyl)carbamate (CAS 478067-15-1)
- 2-(4-Chlorobenzenesulfonamido)-N-[3-(trifluoromethyl)phenyl]propanamide (CAS 1008261-45-7)
- Methyl 2-[2-(4-chlorobenzenesulfonamido)acetamido]-4-(methylsulfanyl)butanoate (CAS 1008068-65-2)
- 2-(4-Chlorobenzenesulfonamido)ethyl N-(4-chlorophenyl)carbamate (CAS 478066-88-5)
Recommended Standards
- (S)-4-((2-(3-Chlorophenyl)-2-hydroxyethyl)amino)-3-(4-methyl-6-morpholino-1H-benzo[d]imidazol-2-yl)pyridin-2(1H)-one (CAS 468740-43-4)
- SANT-2 (CAS 329196-48-7)
- Methyl 4-(4-chlorophenyl)-3-(N-(4-(ethoxycarbonyl)phenyl)sulfamoyl)thiophene-2-carboxylate (CAS 1021209-52-8)
- Desbenzyl N-Acetyl-di-O-acetyl KRP-203 (CAS 951238-24-7)
- 5-(Piperazin-1-yl)-2-(trifluoromethyl)-1,6-naphthyridine (CAS 890302-17-7)
- N-((1-Cyclohexyl-1H-tetrazol-5-yl)methyl)propane-1-sulfonamide (CAS 921125-25-9)
- 4-Chloro-2-(1-isopropyl-piperidin-4-yl)-6-methyl-pyrimidine (CAS 1316218-47-9)
- (R)-3-(1-Methyl-1H-indol-3-yl)-butanal (R)-3-(1-methyl-1H-indol-3-yl)butanal 405873-05-4 (CAS 405873-05-4)
- 8-(Β-D-Glucopyranosyloxy)-7-Hydroxy-2H-1-Benzopyran-2-One (CAS 20853-56-9)
- 2-Oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepine-7-sulfonamide (CAS 1340487-11-7)
- (3-Chloro-5-(trifluoromethyl)pyridin-2-yl)(4-methoxyphenyl)methanol (CAS 321432-48-8)
- 1,1,1-Trifluoro-3-(4-methoxyphenyl)propan-2-one (CAS 22102-10-9)
- Ethyl 6-amino-5-cyano-4-(4-fluorophenyl)-2-[(phenylsulfanyl)methyl]-4H-pyran-3-carboxylate (CAS 478260-22-9)
- Peptide Impurity 34 (CAS 21282-09-7)
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