2-Amino-4-(propan-2-ylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile CAS 478067-17-3
| CAS No. | 478067-17-3 |
| Molecular Formula | C12H12N4S2 |
| Molecular Weight | 276.38 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
Under current pharmacopoeial and regulatory frameworks, quality-control requirements for this class of reference material explicitly involve the control of targets including 2-Amino-4-(propan-2-ylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile.
2-Amino-4-(propan-2-ylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile (CAS 478067-17-3), molecular formula C12H12N4S2 and molecular weight 276.38 g/mol, is a CATO reference standard with documented purity and traceability.
Structurally, 2-Amino-4-(propan-2-ylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile (C12H12N4S2) contains a nitrogen-containing heterocyclic scaffold, a nitrile group, sulfur-containing functionality. The molecule exhibits a degree of unsaturation (DBE) of 9.0, corresponding to approximately 9 ring(s) or double-bond equivalent(s). With a molecular weight of 276.38 g/mol, it falls into the medium-molecular-weight range. The presence of an aromatic ring or conjugated system gives the compound characteristic absorption bands in the UV-Vis region, making it well suited to UV or diode-array detection (DAD).
Recommended for analytical method development and validation; each product is supplied with a full Certificate of Analysis (COA) ensuring ISO 17034 metrological traceability.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C12H12N4S2 |
| Molecular Weight | 276.38 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 4 |
| Sulfur Atoms | 2 |
Related Amino Standards
- 2-Amino-4-(propylsulfanyl)-6-(thiophen-2-yl)pyrimidine-5-carbonitrile (CAS 478067-19-5)
- 7-Amino-5-isopentyl-3,3-dimethyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5h)-one (CAS 1170834-00-0)
- 8-Amino-5-isopentyl-3,3-dimethyl-2,3-dihydrobenzo[b][1,4]oxazepin-4(5h)-one (CAS 1170921-93-3)
- 1-Boc-6-amino-4,4-dimethyl-3,4-dihydro-2H-quinoline (CAS 1187933-54-5)
- Ethyl 3-amino-4-[cyclohexyl(methyl)amino]benzoate (CAS 1219967-38-0)
- Ethyl 3-amino-4-(2-ethyl-1-piperidinyl)benzoate (CAS 1220027-78-0)
- Ethyl 3-amino-4-(3,5-dimethylpiperidin-1-yl)benzoate (CAS 1304304-97-9)
- (S)-2-Amino-N-cyclopropyl-N-(2-methoxybenzyl)-3-methylbutanamide (CAS 1306108-26-8)
Recommended Standards
- 2,3-Dibromo-5-chlorothiophene (CAS 60404-19-5)
- 2,2-Diethyl-4,5-diphenyl-2H-imidazole (CAS 55682-35-4)
- 3-(3-Ethyl-1H-indol-2-yl)-5,6,7,8-tetrahydroisoquinoline (CAS 574-60-7)
- 1-Benzyl-4-phenylpiperidine-4-carbonitrile (CAS 56243-25-5)
- Dimethyl-1,3-thiazole-2-sulfonamide (CAS 1849338-77-7)
- Ethyl 4-chloro-6-methoxy-5-nitronicotinate (CAS 1210835-76-9)
- 2,4-Dichloroquinolin-5-amine (CAS 2091462-77-8)
- 3-Phenyl-1,2-oxazol-5-yl 4-chlorobenzoate (CAS 224566-03-4)
- N1,N1-Dimethyl-N2-((3-methyl-1-propyl-1H-pyrazol-4-yl)methyl)ethane-1,2-diamine dihydrochloride (CAS 1856035-89-6)
- 6-Methoxy-2,3-dihydrospiro[1-benzopyran-4,1'-cyclopropane]-2'-carboxylic acid (CAS 1780014-73-4)
- (R)-3-(4-((4'-(Trifluoromethyl)-[1,1'-biphenyl]-3-yl)methoxy)phenyl)hex-4-ynoic acid (CAS 1638744-77-0)
- 1-Bromo-4-cyclopropylmethanesulfonyl-benzene (CAS 144461-23-4)
- tert-Butyl 7-bromo-1,2-dihydrospiro[indole-3,4'-piperidine]-1'-carboxylate (CAS 1128133-41-4)
- Semaglutide Impurity 131 (CAS 2618647-80-4)
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