4-Methyl-2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydroquinazoline CAS 478067-72-0
| CAS No. | 478067-72-0 |
| Molecular Formula | C13H19N3 |
| Molecular Weight | 217.31 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
Chemical Structure
Description
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
4-Methyl-2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydroquinazoline (CAS 478067-72-0) is a high-purity analytical reference standard with the molecular formula C13H19N3 and a molecular weight of 217.31 g/mol.
Owing to a nitrogen-containing heterocyclic scaffold, a nitrile group, 4-Methyl-2-(pyrrolidin-1-yl)-5,6,7,8-tetrahydroquinazoline is typically off-white to pale yellow low-melting solid. Its solid-state physicochemical attributes — including a molecular weight of 217.31 g/mol — guide the selection of appropriate sample preparation and analytical techniques. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H19N3 |
| Molecular Weight | 217.31 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 6.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Nitrogen Atoms | 3 |
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Recommended Standards
- 4-Heptoxybenzonitrile (CAS 29147-88-4)
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- 5-[[(Tetrahydro-2-furanyl)methyl]amino]-1,3,4-thiadiazole-2(3H)-thione (CAS 871673-10-8)
- 2-Hydroxy-2,4-dimethyl-2,3-dihydro-1-benzofuran-3-one (CAS 372119-01-2)
- tert-Butyl (2-((tert-butoxycarbonyl)amino)ethyl)(2-hydroxyethyl)carbamate (CAS 200283-08-5)
- 3-Ethynyl-2-methoxypyridin-4-amine (CAS 1824109-02-5)
- Phloroglucinol Impurity 28 (CAS 500-99-2)
- (E)-3-(4-chlorophenyl)-3-oxopropanal O-methyl oxime (CAS 339021-13-5)
- 4-Methyl-5-oxo-4,5-dihydro-1H-pyrazole-3-carboxylic acid (CAS 343929-13-5)
- 2-Chloro-4-hydrazinylbenzoic acid hydrochloride (CAS 41112-74-7)
- Lefamulinum Impurity 10 (CAS CATO-C4X-304710)
- 4-(1-methyl-1H-1,2,4-triazol-5-yl)benzoic acid (CAS 1067613-97-1)
- Peptide Impurity 11 X TFA Salt (CAS CATO-CPTD788811)
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