| CAS No. | 478067-99-1 |
| Molecular Formula | C12H7ClF3N3OS |
| Molecular Weight | 333.72 g/mol |
| Category | Pharmaceutical Standards / API Standards |
| Availability | In Stock |
N'-[(1E)-(2-Chloro-1,3-thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzohydrazide (CAS 478067-99-1) is a high-purity analytical reference standard with the molecular formula C12H7ClF3N3OS and a molecular weight of 333.72 g/mol.
N'-[(1E)-(2-Chloro-1,3-thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzohydrazide (C12H7ClF3N3OS) contains a nitrogen-containing heterocyclic scaffold, an amide group, sulfur-containing functionality, a hydroxyl group, an ether linkage, fluorine/chlorine substitution. Halogen substitution raises its density and boiling point, its high carbon-to-hydrogen ratio confers good lipid solubility; these physicochemical properties determine the optimal preparation and storage of its standard solutions. Halogen substitution (F/Cl/Br/I) produces a distinctive isotope pattern in mass spectrometry, a valuable aid for qualitative confirmation.
This reference standard is suitable for quantitative analysis on major chromatographic platforms including HPLC, GC, LC-MS/MS, and GC-MS, serving as an external calibration standard or a system suitability test reference material.
CATO manufactures N'-[(1E)-(2-Chloro-1,3-thiazol-5-yl)methylidene]-4-(trifluoromethyl)benzohydrazide under ISO 17034:2016 accreditation with dual CNAS and ANAB accreditation. Each batch is characterized by orthogonal methods and supplied with a full Certificate of Analysis (COA), ensuring metrological traceability.
| Molecular Formula | C12H7ClF3N3OS |
| Molecular Weight | 333.72 g/mol |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light |
| Degree of Unsaturation (DBE) | 9.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| CAS Registry Year (est.) | 2025 |
| Halogen Content | F/Cl-containing |
| Nitrogen Atoms | 3 |
| Sulfur Atoms | 1 |